Cymbalta and Eyelid twitch - a phase IV clinical study of FDA data

Summary:

Eyelid twitch is reported as a side effect among people who take Cymbalta (duloxetine hydrochloride), especially for people who are female, 40-49 old, have been taking the drug for < 1 month also take Xyrem, and have Narcolepsy.

The phase IV clinical study analyzes which people have Eyelid twitch when taking Cymbalta. It is created by eHealthMe based on reports of 145,249 people who have side effects when taking Cymbalta from the FDA, and is updated regularly.

What is Cymbalta?

Cymbalta has active ingredients of duloxetine hydrochloride. It is often used in depression. eHealthMe is studying from 154,973 Cymbalta users. Check the latest studies of Cymbalta.

What is Eyelid twitch?

Eyelid twitch (spontaneous and uncontrolled spasms of the muscles) is found to be associated with 528 drugs and 959 conditions by eHealthMe. Check the latest studies of Eyelid twitch.

On May, 06, 2026

145,249 people reported to have side effects when taking Cymbalta.
Among them, 67 people (0.05%) have Eyelid twitch.

Among these 67 people:

How long have people been on Cymbalta when they have Eyelid twitch? *

What is the gender of people who have Eyelid twitch when taking Cymbalta? *

female: 90.91 %
male: 9.09 %

What is the age of people who have Eyelid twitch when taking Cymbalta? *

What are other drugs people take besides Cymbalta? *

What are other side effects people have besides Eyelid twitch? *

Dizziness: 19 people, 28.36%
Fatigue (feeling of tiredness): 16 people, 23.88%
Headache (pain in head): 13 people, 19.40%
Nausea (feeling of having an urge to vomit): 12 people, 17.91%
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect): 11 people, 16.42%
Weight Increased: 9 people, 13.43%
Pharyngitis Streptococcal (inflammation of the pharynx caused by infection from. streptococcus): 8 people, 11.94%
Malaise (a feeling of general discomfort or uneasiness): 8 people, 11.94%
Feeling Abnormal: 8 people, 11.94%
Confusional State: 8 people, 11.94%

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 10 people, 14.93%
Pain: 9 people, 13.43%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 7 people, 10.45%
Immunodeficiency Common Variable: 6 people, 8.96%
Indigestion: 6 people, 8.96%
Drowsiness: 5 people, 7.46%
High Blood Cholesterol: 3 people, 4.48%
Insomnia (sleeplessness): 3 people, 4.48%
Migraine (headache): 3 people, 4.48%
Abdominal Pain Upper: 3 people, 4.48%

* Approximation only. Some reports may have incomplete information.

Do you take Cymbalta and have Eyelid twitch?

- Check whether Eyelid twitch is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Cymbalta:

Cymbalta (154,973 reports)

Eyelid twitch treatments and more:

Eyelid twitch (7,214 reports)

Browse all side effects of Cymbalta:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Eyelid twitch:

Eyelid twitch (528 drugs)

Browse all the conditions that are associated with Eyelid twitch:

Eyelid twitch (959 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on duloxetine hydrochloride (the active ingredients of Cymbalta) and Cymbalta (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.