Cymbalta and Unilateral hydronephrosis - a phase IV clinical study of FDA data

Summary:

Unilateral hydronephrosis is reported as a side effect among people who take Cymbalta (duloxetine hydrochloride), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Zometa, and have Multiple sclerosis.

The phase IV clinical study analyzes which people have Unilateral hydronephrosis when taking Cymbalta. It is created by eHealthMe based on reports of 145,249 people who have side effects when taking Cymbalta from the FDA, and is updated regularly.

What is Cymbalta?

Cymbalta has active ingredients of duloxetine hydrochloride. It is often used in depression. eHealthMe is studying from 154,973 Cymbalta users. Check the latest studies of Cymbalta.

What is Unilateral hydronephrosis?

Unilateral hydronephrosis (kidney stone that causes obstruction of the ureter) is found to be associated with 1,010 drugs and 1,193 conditions by eHealthMe. Check the latest studies of Unilateral hydronephrosis.

On Jul, 19, 2026

145,249 people reported to have side effects when taking Cymbalta.
Among them, 99 people (0.07%) have Unilateral hydronephrosis.

Could Cymbalta cause Unilateral hydronephrosis?

Among these 99 people:

How long have people been on Cymbalta when they have Unilateral hydronephrosis? *

What is the gender of people who have Unilateral hydronephrosis when taking Cymbalta? *

female: 75.26 %
male: 24.74 %

What is the age of people who have Unilateral hydronephrosis when taking Cymbalta? *

What are other drugs people take besides Cymbalta? *

What are other side effects people have besides Unilateral hydronephrosis? *

Pain: 35 people, 35.35%
Abdominal Pain: 34 people, 34.34%
Kidney Stones: 34 people, 34.34%
Dyspnea (difficult or laboured breathing): 32 people, 32.32%
Back Pain: 31 people, 31.31%
Hypoaesthesia (reduced sense of touch or sensation): 30 people, 30.30%
Osteonecrosis Of Jaw (death of bone of jaw): 29 people, 29.29%
Osteoporosis (bones weak and more likely to break): 29 people, 29.29%
Spinal Osteoarthritis (joint cartilage loss in spine): 29 people, 29.29%
Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 28 people, 28.28%

What are the existing conditions these people have? *

Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 31 people, 31.31%
Pain: 26 people, 26.26%
Osteoporosis (bones weak and more likely to break): 13 people, 13.13%
Nausea (feeling of having an urge to vomit): 10 people, 10.10%
Multiple Myeloma (cancer of the plasma cells): 10 people, 10.10%
Metastases To Bone (cancer spreads to bone): 8 people, 8.08%
Sleep Disorder: 6 people, 6.06%
High Blood Pressure: 6 people, 6.06%
Muscle Spasms (muscle contraction): 5 people, 5.05%
Multiple Sclerosis Relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 5 people, 5.05%

* Approximation only. Some reports may have incomplete information.

Do you take Cymbalta and have Unilateral hydronephrosis?

- Check whether Unilateral hydronephrosis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Cymbalta:

Cymbalta (154,973 reports)

Browse all side effects of Cymbalta:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Unilateral hydronephrosis:

Unilateral hydronephrosis (1,010 drugs)

Browse all the conditions that are associated with Unilateral hydronephrosis:

Unilateral hydronephrosis (1,193 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on duloxetine hydrochloride (the active ingredients of Cymbalta) and Cymbalta (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.