Cymbalta and Walking disability - a phase IV clinical study of FDA data

Summary:

Walking disability is reported as a side effect among people who take Cymbalta (duloxetine hydrochloride), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Lyrica, and have Neuropathy peripheral.

The phase IV clinical study analyzes which people have Walking disability when taking Cymbalta. It is created by eHealthMe based on reports of 145,249 people who have side effects when taking Cymbalta from the FDA, and is updated regularly.

What is Cymbalta?

Cymbalta has active ingredients of duloxetine hydrochloride. It is often used in depression. eHealthMe is studying from 154,968 Cymbalta users. Check the latest studies of Cymbalta.

What is Walking disability?

Walking disability is found to be associated with 303 drugs and 806 conditions by eHealthMe. Check the latest studies of Walking disability.

On Feb, 03, 2026

145,249 people reported to have side effects when taking Cymbalta.
Among them, 28 people (0.02%) have Walking disability.

Could Cymbalta cause Walking disability?

Among these 28 people:

How long have people been on Cymbalta when they have Walking disability? *

What is the gender of people who have Walking disability when taking Cymbalta? *

female: 71.43 %
male: 28.57 %

What is the age of people who have Walking disability when taking Cymbalta? *

What are other drugs people take besides Cymbalta? *

What are other side effects people have besides Walking disability? *

Pain: 14 people, 50.00%
Drug Ineffective: 9 people, 32.14%
Diplopia (double vision): 7 people, 25.00%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 5 people, 17.86%
Rashes (redness): 5 people, 17.86%
Muscle Rigidity (muscle stiffness): 5 people, 17.86%
Back Pain: 5 people, 17.86%
Oedema Peripheral (superficial swelling): 5 people, 17.86%
Mental Disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability): 4 people, 14.29%
Joint Pain: 4 people, 14.29%

What are the existing conditions these people have? *

Neuropathy Peripheral (surface nerve damage): 7 people, 25.00%
Complex Regional Pain Syndrome (long lasting pain condition most often affecting one of the limbs (arms, legs, hands, or feet)): 5 people, 17.86%
Pain: 4 people, 14.29%
Lung Neoplasm Malignant (cancer tumour of lung): 4 people, 14.29%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 14.29%
Major Depression (a mood state that goes well beyond temporarily feeling sad or blue. it is a serious medical illness that affects one's thoughts, feelings): 3 people, 10.71%
Pain In Extremity: 3 people, 10.71%
Drowsiness: 3 people, 10.71%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 3 people, 10.71%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 3 people, 10.71%

* Approximation only. Some reports may have incomplete information.

Do you take Cymbalta and have Walking disability?

- Check whether Walking disability is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Cymbalta:

Cymbalta (154,968 reports)

Browse all side effects of Cymbalta:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Walking disability:

Walking disability (303 drugs)

Browse all the conditions that are associated with Walking disability:

Walking disability (806 conditions)

Drugs similar to Cymbalta and Walking disability :

How the study uses the data?

The study uses data from the FDA. It is based on duloxetine hydrochloride (the active ingredients of Cymbalta) and Cymbalta (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.