Cytomel and Joint swelling - a phase IV clinical study of FDA data

Summary:

Joint swelling is reported as a side effect among people who take Cytomel (liothyronine sodium), especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months also take Synthroid, and have Rheumatoid arthritis.

The phase IV clinical study analyzes which people have Joint swelling when taking Cytomel. It is created by eHealthMe based on reports of 6,807 people who have side effects when taking Cytomel from the FDA, and is updated regularly.

What is Cytomel?

Cytomel has active ingredients of liothyronine sodium. It is often used in hypothyroidism. eHealthMe is studying from 7,595 Cytomel users. Check the latest studies of Cytomel.

What is Joint swelling?

Joint swelling is found to be associated with 2,123 drugs and 2,934 conditions by eHealthMe. Check the latest studies of Joint swelling.

On May, 31, 2026

6,807 people reported to have side effects when taking Cytomel.
Among them, 71 people (1.04%) have Joint swelling.

Among these 71 people:

How long have people been on Cytomel when they have Joint swelling? *

What is the gender of people who have Joint swelling when taking Cytomel? *

female: 89.47 %
male: 10.53 %

What is the age of people who have Joint swelling when taking Cytomel? *

What are other drugs people take besides Cytomel? *

What are other side effects people have besides Joint swelling? *

Joint Pain: 29 people, 40.85%
Weight Increased: 23 people, 32.39%
Peripheral Swelling: 23 people, 32.39%
Pain: 22 people, 30.99%
Headache (pain in head): 19 people, 26.76%
Dyspnea (difficult or laboured breathing): 14 people, 19.72%
Fatigue (feeling of tiredness): 14 people, 19.72%
Feeling Abnormal: 12 people, 16.90%
Nausea (feeling of having an urge to vomit): 11 people, 15.49%
Pain In Extremity: 11 people, 15.49%

What are the existing conditions these people have? *

Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 9 people, 12.68%
High Blood Cholesterol: 6 people, 8.45%
Hypersensitivity: 6 people, 8.45%
Insomnia (sleeplessness): 6 people, 8.45%
High Blood Pressure: 5 people, 7.04%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 7.04%
Migraine (headache): 5 people, 7.04%
Polycythaemia Vera (blood disorder in which the bone marrow makes too many red blood cells): 5 people, 7.04%
Stress And Anxiety: 4 people, 5.63%
Fabry's Disease (build up of a particular type of fat, called globotriaosylceramide, in the body's cells): 4 people, 5.63%

* Approximation only. Some reports may have incomplete information.

Do you take Cytomel and have Joint swelling?

- Check whether Joint swelling is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Cytomel:

Cytomel (7,595 reports)

Joint swelling treatments and more:

Joint swelling (143,797 reports)

Browse all side effects of Cytomel:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Joint swelling:

Joint swelling (2,123 drugs)

Browse all the conditions that are associated with Joint swelling:

Joint swelling (2,934 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on liothyronine sodium (the active ingredients of Cytomel) and Cytomel (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.