Dacogen and Cardiac failure aggravated - a phase IV clinical study of FDA data

Summary:

Cardiac failure aggravated is reported as a side effect among people who take Dacogen (decitabine), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Cytarabine, and have Myelodysplastic syndrome.

The phase IV clinical study analyzes which people have Cardiac failure aggravated when taking Dacogen. It is created by eHealthMe based on reports of 1,535 people who have side effects when taking Dacogen from the FDA, and is updated regularly.

What is Dacogen?

Dacogen has active ingredients of decitabine. eHealthMe is studying from 1,541 Dacogen users. Check the latest studies of Dacogen.

What is Cardiac failure aggravated?

Cardiac failure aggravated is found to be associated with 1,826 drugs and 760 conditions by eHealthMe. Check the latest studies of Cardiac failure aggravated.

On Jul, 28, 2026

1,535 people reported to have side effects when taking Dacogen.
Among them, 16 people (1.04%) have Cardiac failure aggravated.

Could Dacogen cause Cardiac failure aggravated?

Among these 16 people:

How long have people been on Dacogen when they have Cardiac failure aggravated? *

What is the gender of people who have Cardiac failure aggravated when taking Dacogen? *

female: 50 %
male: 50 %

What is the age of people who have Cardiac failure aggravated when taking Dacogen? *

What are other drugs people take besides Dacogen? *

What are other side effects people have besides Cardiac failure aggravated? *

Respiratory Acidosis (respiratory failure or ventilatory failure, causes the ph of blood and other bodily fluids to decrease): 4 people, 25.00%
Pneumonia: 4 people, 25.00%
Lung Infection: 3 people, 18.75%
Cardiogenic Shock (inadequate circulation of blood): 3 people, 18.75%
Cough: 3 people, 18.75%
Coughing Up Blood: 3 people, 18.75%
Heart Attack: 3 people, 18.75%
Productive Cough: 3 people, 18.75%
Malaise (a feeling of general discomfort or uneasiness): 2 people, 12.50%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 2 people, 12.50%

What are the existing conditions these people have? *

Myelodysplastic Syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged): 9 people, 56.25%
Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 3 people, 18.75%
Polycythemia Vera (blood disorder in which the bone marrow makes too many red blood cells): 1 person, 6.25%
Acute Myelomonocytic Leukaemia (cancer of the blood-forming organs): 1 person, 6.25%

* Approximation only. Some reports may have incomplete information.

Do you take Dacogen and have Cardiac failure aggravated?

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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Dacogen:

Dacogen (1,541 reports)

Browse all side effects of Dacogen:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Cardiac failure aggravated:

Cardiac failure aggravated (1,826 drugs)

Browse all the conditions that are associated with Cardiac failure aggravated:

Cardiac failure aggravated (760 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on decitabine (the active ingredients of Dacogen) and Dacogen (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.