Dactinomycin and Chills - a phase IV clinical study of FDA data

Summary:

Chills is reported as a side effect among people who take Dactinomycin (dactinomycin), especially for people who are male, 10-19 old, have been taking the drug for < 1 month also take Ifosfamide, and have Ewing's sarcoma.

The phase IV clinical study analyzes which people have Chills when taking Dactinomycin. It is created by eHealthMe based on reports of 2,575 people who have side effects when taking Dactinomycin from the FDA, and is updated regularly.

What is Dactinomycin?

Dactinomycin has active ingredients of dactinomycin. eHealthMe is studying from 2,577 Dactinomycin users. Check the latest studies of Dactinomycin.

What is Chills?

Chills (felling of cold) is found to be associated with 2,549 drugs and 3,475 conditions by eHealthMe. Check the latest studies of Chills.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Aug, 30, 2026

2,575 people reported to have side effects when taking Dactinomycin.
Among them, 11 people (0.43%) have Chills.

Could Dactinomycin cause Chills?

Among these 11 people:

How long have people been on Dactinomycin when they have Chills? *

  • < 1 month: 66.67 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 33.33 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Chills when taking Dactinomycin? *

  • female: 18.18 %
  • male: 81.82 %

What is the age of people who have Chills when taking Dactinomycin? *

  • 0-1: 0.0 %
  • 2-9: 11.11 %
  • 10-19: 44.44 %
  • 20-29: 11.11 %
  • 30-39: 33.33 %
  • 40-49: 0.0 %
  • 50-59: 0.0 %
  • 60+: 0.0 %

What are other drugs people take besides Dactinomycin? *

  1. Ifosfamide: 6 people, 54.55%
  2. Cyclophosphamide: 5 people, 45.45%
  3. Trimethoprim: 4 people, 36.36%
  4. Morphine Sulfate: 4 people, 36.36%
  5. Ondansetron: 4 people, 36.36%
  6. Sulfamethoxazole: 4 people, 36.36%
  7. Sodium Chloride: 4 people, 36.36%
  8. Potassium Chloride: 3 people, 27.27%
  9. Paracetamol: 3 people, 27.27%
  10. Lactulose: 3 people, 27.27%

What are other side effects people have besides Chills? *

  1. Fever: 7 people, 63.64%
  2. Febrile Neutropenia (fever with reduced white blood cells): 5 people, 45.45%
  3. Headache (pain in head): 4 people, 36.36%
  4. Fainting (loss of consciousness and postural tone): 3 people, 27.27%
  5. Thrombocytopenia (decrease of platelets in blood): 3 people, 27.27%
  6. Sepsis (a severe blood infection that can lead to organ failure and death): 3 people, 27.27%
  7. Arrhythmias (irregular heartbeat): 3 people, 27.27%
  8. Presyncope: 3 people, 27.27%
  9. Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 2 people, 18.18%
  10. Dizziness: 2 people, 18.18%

What are the existing conditions these people have? *

  1. Ewing's Sarcoma (malignant small, round, blue cell tumour): 4 people, 36.36%
  2. Neoplasm Malignant (cancer tumour): 3 people, 27.27%
  3. Tumor: 1 person, 9.09%
  4. Rhabdomyosarcoma (cancer of the bone, soft tissues, or connective tissue (e.g., tendon or cartilage)): 1 person, 9.09%
  5. Refractory Cancer (cancer that has not responded to treatment): 1 person, 9.09%
  6. Recurrent Cancer (repeated cancer): 1 person, 9.09%
  7. Proctalgia (pain in the rectum): 1 person, 9.09%
  8. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 1 person, 9.09%
  9. Haemorrhoids (a swollen vein or group of veins in the region of the anus): 1 person, 9.09%
  10. Adverse Event: 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Dactinomycin and have Chills?

- Check whether Chills is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Dactinomycin:

Chills treatments and more:

How severe was Chills and when was it recovered:

Expand to all the drugs that have ingredients of dactinomycin:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Dactinomycin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Chills:

Browse all the conditions that are associated with Chills:


How the study uses the data?

The study uses data from the FDA. It is based on dactinomycin (the active ingredients of Dactinomycin) and Dactinomycin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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