Daliresp and Cardiac failure aggravated - a phase IV clinical study of FDA data

Summary:

Cardiac failure aggravated is reported as a side effect among people who take Daliresp (roflumilast), especially for people who are female, 60+ old, also take Spiriva, and have Type 2 diabetes.

The phase IV clinical study analyzes which people have Cardiac failure aggravated when taking Daliresp. It is created by eHealthMe based on reports of 4,674 people who have side effects when taking Daliresp from the FDA, and is updated regularly.

What is Daliresp?

Daliresp has active ingredients of roflumilast. It is often used in chronic obstructive pulmonary disease. eHealthMe is studying from 4,722 Daliresp users. Check the latest studies of Daliresp.

What is Cardiac failure aggravated?

Cardiac failure aggravated is found to be associated with 1,820 drugs and 760 conditions by eHealthMe. Check the latest studies of Cardiac failure aggravated.

On Jul, 08, 2026

4,674 people reported to have side effects when taking Daliresp.
Among them, 17 people (0.36%) have Cardiac failure aggravated.

Could Daliresp cause Cardiac failure aggravated?

Among these 17 people:

What is the gender of people who have Cardiac failure aggravated when taking Daliresp? *

female: 60 %
male: 40 %

What is the age of people who have Cardiac failure aggravated when taking Daliresp? *

What are other drugs people take besides Daliresp? *

What are other side effects people have besides Cardiac failure aggravated? *

Heart Attack: 5 people, 29.41%
Dyspnea (difficult or laboured breathing): 4 people, 23.53%
Lung Disorder (lung disease): 3 people, 17.65%
Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 3 people, 17.65%
Fatigue (feeling of tiredness): 2 people, 11.76%
Arteriosclerosis Coronary Artery (thickening and hardening of arteries- coronary artery): 2 people, 11.76%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 2 people, 11.76%
Cardiac Failure Congestive: 2 people, 11.76%
Chest Pain: 2 people, 11.76%
Drug Hypersensitivity: 2 people, 11.76%

What are the existing conditions these people have? *

Type 2 Diabetes: 2 people, 11.76%
Stress And Anxiety: 1 person, 5.88%
Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 1 person, 5.88%
Myelodysplastic Syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged): 1 person, 5.88%
Muscle Spasms (muscle contraction): 1 person, 5.88%
Metastatic Renal Cell Carcinoma (spreadable kidney cell tumour): 1 person, 5.88%
Itching: 1 person, 5.88%
Immunodeficiency Common Variable: 1 person, 5.88%
Hypogammaglobulinaemia (an abnormally low concentration of gamma globulin in the blood and increased risk of infection): 1 person, 5.88%
High Blood Pressure: 1 person, 5.88%

* Approximation only. Some reports may have incomplete information.

Do you take Daliresp and have Cardiac failure aggravated?

- Check whether Cardiac failure aggravated is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Daliresp:

Daliresp (4,722 reports)

Browse all side effects of Daliresp:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Cardiac failure aggravated:

Cardiac failure aggravated (1,820 drugs)

Browse all the conditions that are associated with Cardiac failure aggravated:

Cardiac failure aggravated (760 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on roflumilast (the active ingredients of Daliresp) and Daliresp (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.