Dantrium and Coma - a phase IV clinical study of FDA data

Summary:

Coma is reported as a side effect among people who take Dantrium (dantrolene sodium), especially for people who are male, 50-59 old, have been taking the drug for < 1 month also take Reglan, and have Multiple sclerosis.

The phase IV clinical study analyzes which people have Coma when taking Dantrium. It is created by eHealthMe based on reports of 1,397 people who have side effects when taking Dantrium from the FDA, and is updated regularly.

What is Dantrium?

Dantrium has active ingredients of dantrolene sodium. eHealthMe is studying from 1,408 Dantrium users. Check the latest studies of Dantrium.

What is Coma?

Coma (state of unconsciousness lasting more than six hours) is found to be associated with 2,762 drugs and 3,209 conditions by eHealthMe. Check the latest studies of Coma.



On Jun, 21, 2026

1,397 people reported to have side effects when taking Dantrium.
Among them, 11 people (0.79%) have Coma.

Could Dantrium cause Coma?

Among these 11 people:

How long have people been on Dantrium when they have Coma? *

  • < 1 month: 66.67 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 33.33 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Coma when taking Dantrium? *

  • female: 27.27 %
  • male: 72.73 %

What is the age of people who have Coma when taking Dantrium? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 30 %
  • 40-49: 0.0 %
  • 50-59: 60 %
  • 60+: 10 %

What are other drugs people take besides Dantrium? *

  1. Ms Contin: 2 people, 18.18%
  2. Paxil: 2 people, 18.18%
  3. Avonex: 2 people, 18.18%
  4. Baclofen: 2 people, 18.18%
  5. Bextra: 2 people, 18.18%
  6. Vicodin: 2 people, 18.18%
  7. Actiq: 2 people, 18.18%
  8. Provigil: 2 people, 18.18%
  9. Reglan: 2 people, 18.18%
  10. Prilosec: 1 person, 9.09%

What are other side effects people have besides Coma? *

  1. Hypotension (abnormally low blood pressure): 4 people, 36.36%
  2. Pneumonia: 3 people, 27.27%
  3. Blood Sodium Decreased: 2 people, 18.18%
  4. Confusional State: 2 people, 18.18%
  5. Bradycardia (abnormally slow heart action): 2 people, 18.18%
  6. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 2 people, 18.18%
  7. Grand Mal Convulsion (a type of generalized seizure that affects the entire brain): 2 people, 18.18%
  8. Blood Creatine Phosphokinase Increased: 2 people, 18.18%
  9. Lactic Acidosis (low ph in body tissues): 2 people, 18.18%
  10. Enlarged Heart: 1 person, 9.09%

What are the existing conditions these people have? *

  1. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 4 people, 36.36%
  2. Myoclonus (a brief, involuntary twitching of a muscle or a group of muscles): 1 person, 9.09%
  3. Muscle Spasticity (tight or stiff muscles and an inability to control those muscles): 1 person, 9.09%
  4. Muscle Spasms (muscle contraction): 1 person, 9.09%
  5. Movement - Uncontrolled Or Slow: 1 person, 9.09%
  6. Hyperpyrexia Malignant (disease passed down through families that causes a fast rise in body temperature (fever) and severe muscle contractions- infectious): 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Dantrium and have Coma?

- Check whether Coma is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Dantrium:

Coma treatments and more:

  • Coma (57,420 reports)

How severe was Coma and when was it recovered:

Expand to all the drugs that have ingredients of dantrolene sodium:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Dantrium:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Coma:

  • Coma (2,762 drugs)

Browse all the conditions that are associated with Coma:

  • Coma (3,209 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on dantrolene sodium (the active ingredients of Dantrium) and Dantrium (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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