Dapsone and Gastroesophageal reflux disease - a phase IV clinical study of FDA data

Summary:

Gastroesophageal reflux disease is reported as a side effect among people who take Dapsone (dapsone), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Nexium, and have Osteoporosis.

The phase IV clinical study analyzes which people have Gastroesophageal reflux disease when taking Dapsone. It is created by eHealthMe based on reports of 11,499 people who have side effects when taking Dapsone from the FDA, and is updated regularly.

What is Dapsone?

Dapsone has active ingredients of dapsone. It is often used in dermatitis herpetiformis. eHealthMe is studying from 11,732 Dapsone users. Check the latest studies of Dapsone.

What is Gastroesophageal reflux disease?

Gastroesophageal reflux disease (a condition in which stomach contents leak backward from the stomach into the oesophagus) is found to be associated with 2,397 drugs and 3,492 conditions by eHealthMe. Check the latest studies of Gastroesophageal reflux disease.

On Jul, 18, 2026

11,499 people reported to have side effects when taking Dapsone.
Among them, 89 people (0.77%) have Gastroesophageal reflux disease.

Could Dapsone cause Gastroesophageal reflux disease?

Among these 89 people:

How long have people been on Dapsone when they have Gastroesophageal reflux disease? *

What is the gender of people who have Gastroesophageal reflux disease when taking Dapsone? *

female: 67.95 %
male: 32.05 %

What is the age of people who have Gastroesophageal reflux disease when taking Dapsone? *

What are other drugs people take besides Dapsone? *

What are other side effects people have besides Gastroesophageal reflux disease? *

Diarrhea: 37 people, 41.57%
Abdominal Pain: 24 people, 26.97%
Nausea (feeling of having an urge to vomit): 22 people, 24.72%
Fall: 21 people, 23.60%
Pain: 21 people, 23.60%
Nausea And Vomiting: 20 people, 22.47%
Fatigue (feeling of tiredness): 19 people, 21.35%
Urinary Tract Infection: 19 people, 21.35%
Weight Loss: 19 people, 21.35%
Gastritis (inflammation of stomach): 18 people, 20.22%

What are the existing conditions these people have? *

Osteoporosis (bones weak and more likely to break): 20 people, 22.47%
Multiple Myeloma (cancer of the plasma cells): 9 people, 10.11%
High Blood Pressure: 7 people, 7.87%
Depression: 6 people, 6.74%
Diabetes: 6 people, 6.74%
High Blood Cholesterol: 6 people, 6.74%
Nausea (feeling of having an urge to vomit): 6 people, 6.74%
Graft Versus Host Disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body): 5 people, 5.62%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 5 people, 5.62%
Asthma: 4 people, 4.49%

* Approximation only. Some reports may have incomplete information.

Do you take Dapsone and have Gastroesophageal reflux disease?

- Check whether Gastroesophageal reflux disease is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Dapsone:

Dapsone (11,732 reports)

Browse all side effects of Dapsone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Gastroesophageal reflux disease:

Gastroesophageal reflux disease (2,397 drugs)

Browse all the conditions that are associated with Gastroesophageal reflux disease:

Gastroesophageal reflux disease (3,492 conditions)

Related publications that referenced our studies

Semira ZA, Zulfkar Q, Sameem F, "Livedo reticularis associated with dapsone therapy in a patient with chronic urticaria", Indian journal of pharmacology, 2014 Jan .
Semira ZA, Zulfkar Q, Sameem F, "Livedo reticularis associated with dapsone therapy in a patient with chronic urticaria", Indian journal of pharmacology, 2014 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on dapsone (the active ingredients of Dapsone) and Dapsone (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.