Dapsone and Herpes simplex aggravated - a phase IV clinical study of FDA data

Summary:

Herpes simplex aggravated is reported as a side effect among people who take Dapsone (dapsone), especially for people who are female, 30-39 old, have been taking the drug for < 1 month also take Methotrexate, and have Behcet's syndrome.

The phase IV clinical study analyzes which people have Herpes simplex aggravated when taking Dapsone. It is created by eHealthMe based on reports of 11,499 people who have side effects when taking Dapsone from the FDA, and is updated regularly.

What is Dapsone?

Dapsone has active ingredients of dapsone. It is often used in dermatitis herpetiformis. eHealthMe is studying from 11,732 Dapsone users. Check the latest studies of Dapsone.

What is Herpes simplex aggravated?

Herpes simplex aggravated (serious herpes simplex is a common viral infection) is found to be associated with 701 drugs and 290 conditions by eHealthMe. Check the latest studies of Herpes simplex aggravated.



On Jul, 22, 2026

11,499 people reported to have side effects when taking Dapsone.
Among them, 24 people (0.21%) have Herpes simplex aggravated.

Could Dapsone cause Herpes simplex aggravated?

Among these 24 people:

How long have people been on Dapsone when they have Herpes simplex aggravated? *

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Herpes simplex aggravated when taking Dapsone? *

  • female: 65.22 %
  • male: 34.78 %

What is the age of people who have Herpes simplex aggravated when taking Dapsone? *

  • 0-1: 0.0 %
  • 2-9: 4.35 %
  • 10-19: 4.35 %
  • 20-29: 21.74 %
  • 30-39: 26.09 %
  • 40-49: 13.04 %
  • 50-59: 17.39 %
  • 60+: 13.04 %

What are other drugs people take besides Dapsone? *

  1. Methotrexate: 5 people, 20.83%
  2. Zithromax: 4 people, 16.67%
  3. Vitamin B6: 4 people, 16.67%
  4. Azathioprine: 4 people, 16.67%
  5. Prednisolone: 4 people, 16.67%
  6. Tylenol: 4 people, 16.67%
  7. Retrovir: 3 people, 12.50%
  8. Acyclovir: 3 people, 12.50%
  9. Diflucan: 3 people, 12.50%
  10. Naprosyn: 3 people, 12.50%

What are other side effects people have besides Herpes simplex aggravated? *

  1. Oral Candidiasis (fungal infection of mouth): 6 people, 25.00%
  2. Lymph Follicular Hypertrophy (an increase in the size of the lymph node follicles): 5 people, 20.83%
  3. Jaundice - Yellow Skin (a yellowish pigmentation of the skin): 4 people, 16.67%
  4. Rashes (redness): 3 people, 12.50%
  5. Pneumonia: 3 people, 12.50%
  6. Hepatic Failure (liver failure): 3 people, 12.50%
  7. Herpes Zoster: 3 people, 12.50%
  8. Folliculitis (infection of hair root): 3 people, 12.50%
  9. Thrombocytopenia (decrease of platelets in blood): 3 people, 12.50%
  10. Fever: 3 people, 12.50%

What are the existing conditions these people have? *

  1. Pemphigus (any of several acute or chronic skin diseases characterized by groups of itching blisters): 2 people, 8.33%
  2. Genital Erosion (ulcer on genital): 2 people, 8.33%
  3. Cytomegalovirus Infection: 2 people, 8.33%
  4. Behcet's Syndrome (involves inflammation of the blood vessels): 2 people, 8.33%
  5. Skin Disorder (skin disease): 1 person, 4.17%
  6. Sinusitis (inflammation of sinus): 1 person, 4.17%
  7. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 4.17%
  8. Plasmablastic Lymphoma (aggressive b-cell cancer occurring mainly in the jaws and oral cavity): 1 person, 4.17%
  9. Pemphigoid (tense blisters on the skin): 1 person, 4.17%
  10. Pain: 1 person, 4.17%

* Approximation only. Some reports may have incomplete information.

Do you take Dapsone and have Herpes simplex aggravated?

- Check whether Herpes simplex aggravated is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Dapsone:

Herpes simplex aggravated treatments and more:

How severe was Herpes simplex aggravated and when was it recovered:

Expand to all the drugs that have ingredients of dapsone:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Dapsone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Herpes simplex aggravated:

Browse all the conditions that are associated with Herpes simplex aggravated:

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on dapsone (the active ingredients of Dapsone) and Dapsone (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe: