Dapsone and Orthostatic hypotension - a phase IV clinical study of FDA data

Summary:

Orthostatic hypotension is reported as a side effect among people who take Dapsone (dapsone), especially for people who are male, 50-59 old, have been taking the drug for < 1 month also take Omeprazole, and have Multiple myeloma.

The phase IV clinical study analyzes which people have Orthostatic hypotension when taking Dapsone. It is created by eHealthMe based on reports of 11,499 people who have side effects when taking Dapsone from the FDA, and is updated regularly.

What is Dapsone?

Dapsone has active ingredients of dapsone. It is often used in dermatitis herpetiformis. eHealthMe is studying from 11,732 Dapsone users. Check the latest studies of Dapsone.

What is Orthostatic hypotension?

Orthostatic hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up) is found to be associated with 1,227 drugs and 1,336 conditions by eHealthMe. Check the latest studies of Orthostatic hypotension.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 31, 2026

11,499 people reported to have side effects when taking Dapsone.
Among them, 11 people (0.1%) have Orthostatic hypotension.

Could Dapsone cause Orthostatic hypotension?

Among these 11 people:

How long have people been on Dapsone when they have Orthostatic hypotension? *

What is the gender of people who have Orthostatic hypotension when taking Dapsone? *

female: 27.27 %
male: 72.73 %

What is the age of people who have Orthostatic hypotension when taking Dapsone? *

What are other drugs people take besides Dapsone? *

What are other side effects people have besides Orthostatic hypotension? *

Dyspnea (difficult or laboured breathing): 6 people, 54.55%
Fainting (loss of consciousness and postural tone): 5 people, 45.45%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 5 people, 45.45%
Heart Palpitations (feelings or sensations that your heart is pounding or racing): 5 people, 45.45%
Loss Of Consciousness: 5 people, 45.45%
Chest Pain: 5 people, 45.45%
Memory Loss: 5 people, 45.45%
Lumbar Spinal Stenosis (a medical condition in which the spinal canal narrows and compresses the spinal cord and nerves at the level of the lumbar bone): 4 people, 36.36%
Joint Pain: 4 people, 36.36%
Head Injury: 4 people, 36.36%

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 3 people, 27.27%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 2 people, 18.18%
Sleep Disorder: 1 person, 9.09%
Pain: 1 person, 9.09%
Lip Injury: 1 person, 9.09%
Hiv Infection: 1 person, 9.09%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 9.09%
Drowsiness: 1 person, 9.09%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 1 person, 9.09%
Acquired Methaemoglobinaemia (a condition that results in the formation of an abnormal form of haemoglobin): 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Dapsone and have Orthostatic hypotension?

- Check whether Orthostatic hypotension is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Dapsone:

Dapsone (11,732 reports)

Browse all side effects of Dapsone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Orthostatic hypotension:

Orthostatic hypotension (1,227 drugs)

Browse all the conditions that are associated with Orthostatic hypotension:

Orthostatic hypotension (1,336 conditions)

Related publications that referenced our studies

Semira ZA, Zulfkar Q, Sameem F, "Livedo reticularis associated with dapsone therapy in a patient with chronic urticaria", Indian journal of pharmacology, 2014 Jan .
Semira ZA, Zulfkar Q, Sameem F, "Livedo reticularis associated with dapsone therapy in a patient with chronic urticaria", Indian journal of pharmacology, 2014 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on dapsone (the active ingredients of Dapsone) and Dapsone (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.