Daptomycin and Acute hepatic failure - a phase IV clinical study of FDA data

Summary:

Acute hepatic failure is reported as a side effect among people who take Daptomycin (daptomycin), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Afinitor, and have Neuroendocrine tumor.

The phase IV clinical study analyzes which people have Acute hepatic failure when taking Daptomycin. It is created by eHealthMe based on reports of 7,865 people who have side effects when taking Daptomycin from the FDA, and is updated regularly.

What is Daptomycin?

Daptomycin has active ingredients of daptomycin. eHealthMe is studying from 7,879 Daptomycin users. Check the latest studies of Daptomycin.

What is Acute hepatic failure?

Acute hepatic failure is found to be associated with 709 drugs and 1,185 conditions by eHealthMe. Check the latest studies of Acute hepatic failure.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

7,865 people reported to have side effects when taking Daptomycin.
Among them, 19 people (0.24%) have Acute hepatic failure.

Could Daptomycin cause Acute hepatic failure?

Among these 19 people:

How long have people been on Daptomycin when they have Acute hepatic failure? *

What is the gender of people who have Acute hepatic failure when taking Daptomycin? *

female: 38.89 %
male: 61.11 %

What is the age of people who have Acute hepatic failure when taking Daptomycin? *

What are other drugs people take besides Daptomycin? *

What are other side effects people have besides Acute hepatic failure? *

Fungal Sepsis (whole body infection by fungus): 6 people, 31.58%
Pleural Effusion (water on the lungs): 6 people, 31.58%
General Physical Health Deterioration (weak health status): 6 people, 31.58%
Rashes (redness): 6 people, 31.58%
Cardiomyopathy (weakening of the heart muscle): 6 people, 31.58%
Pneumothorax (the presence of air or gas in the cavity between the lungs and the chest wall, causing collapse of the lung): 6 people, 31.58%
Infection: 4 people, 21.05%
Cardiovascular Insufficiency (inadequate functioning of heart): 4 people, 21.05%
Diarrhea: 4 people, 21.05%
Respiratory Acidosis (respiratory failure or ventilatory failure, causes the ph of blood and other bodily fluids to decrease): 2 people, 10.53%

What are the existing conditions these people have? *

Neuroendocrine Tumor: 6 people, 31.58%
Staphylococcal Infection (an infection with staphylococcus bacteria): 4 people, 21.05%
Bacteraemia (presence of bacteria in the blood): 4 people, 21.05%
Pulmonary Tuberculosis (lungs tuberculosis): 2 people, 10.53%
Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 2 people, 10.53%
Osteomyelitis (infection of bone): 1 person, 5.26%
Localised Infection (infection at the single location): 1 person, 5.26%
Fever: 1 person, 5.26%
Device Related Infection: 1 person, 5.26%
Bacterial Infection: 1 person, 5.26%

* Approximation only. Some reports may have incomplete information.

Do you take Daptomycin and have Acute hepatic failure?

- Check whether Acute hepatic failure is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Daptomycin:

Daptomycin (7,879 reports)

Browse all side effects of Daptomycin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Acute hepatic failure:

Acute hepatic failure (709 drugs)

Browse all the conditions that are associated with Acute hepatic failure:

Acute hepatic failure (1,185 conditions)

Related publications that referenced our studies

Saliho?lu M, Turhan V, ?nem Y, Ulcay A, Uzun G, Ay H, "Sudden hearing loss in a patient receiving piperacillin/tazobactam and daptomycin for diabetic foot infection", Scandinavian journal of infectious diseases, 2013 Mar .
Saliho?lu M, Turhan V, ?nem Y, Ulcay A, Uzun G, Ay H, "Sudden hearing loss in a patient receiving piperacillin/tazobactam and daptomycin for diabetic foot infection", Scandinavian journal of infectious diseases, 2013 Mar .

How the study uses the data?

The study uses data from the FDA. It is based on daptomycin (the active ingredients of Daptomycin) and Daptomycin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.