Daptomycin and Haemodynamic instability - a phase IV clinical study of FDA data

Summary:

Haemodynamic instability is reported as a side effect among people who take Daptomycin (daptomycin), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Vancomycin, and have Abdominal infection.

The phase IV clinical study analyzes which people have Haemodynamic instability when taking Daptomycin. It is created by eHealthMe based on reports of 7,865 people who have side effects when taking Daptomycin from the FDA, and is updated regularly.

What is Daptomycin?

Daptomycin has active ingredients of daptomycin. eHealthMe is studying from 7,879 Daptomycin users. Check the latest studies of Daptomycin.

What is Haemodynamic instability?

Haemodynamic instability (disturbances in the blood movement in our body) is found to be associated with 557 drugs and 1,272 conditions by eHealthMe. Check the latest studies of Haemodynamic instability.

On Apr, 23, 2026

7,865 people reported to have side effects when taking Daptomycin.
Among them, 38 people (0.48%) have Haemodynamic instability.

Could Daptomycin cause Haemodynamic instability?

Among these 38 people:

How long have people been on Daptomycin when they have Haemodynamic instability? *

What is the gender of people who have Haemodynamic instability when taking Daptomycin? *

female: 8.33 %
male: 91.67 %

What is the age of people who have Haemodynamic instability when taking Daptomycin? *

What are other drugs people take besides Daptomycin? *

Vancomycin: 31 people, 81.58%
Fluconazole: 13 people, 34.21%
Meropenem: 12 people, 31.58%
Linezolid: 12 people, 31.58%
Caspofungin Acetate: 9 people, 23.68%
Piperacillin And Tazobactam: 2 people, 5.26%
Spironolactone: 1 person, 2.63%
Ciprofloxacin: 1 person, 2.63%
Allopurinol: 1 person, 2.63%
Amiodarone Hydrochloride: 1 person, 2.63%

What are other side effects people have besides Haemodynamic instability? *

Sepsis (a severe blood infection that can lead to organ failure and death): 26 people, 68.42%
Upper Gastrointestinal Haemorrhage (upper gastrointestinal bleeding): 25 people, 65.79%
Systemic Inflammatory Response Syndrome (an inflammatory state affecting the whole body, frequently a response of the immune system to infection): 25 people, 65.79%
Spinal Cord Disorder (disease of spinal cord): 25 people, 65.79%
Hypoperfusion (decreased blood flow through an organ): 25 people, 65.79%
Intestinal Ischaemia (decreased supply of oxygenated blood to the intestines): 25 people, 65.79%
Pneumonia: 25 people, 65.79%
Respiratory Tract Infection: 25 people, 65.79%
Rectal Perforation (tear or hole in rectum): 24 people, 63.16%
Death: 22 people, 57.89%

What are the existing conditions these people have? *

Haematoma Infection (infection with collection of blood outside the blood vessels): 25 people, 65.79%
Abdominal Infection: 25 people, 65.79%
Infection: 6 people, 15.79%
Staphylococcal Infection (an infection with staphylococcus bacteria): 3 people, 7.89%
Bacterial Infection: 3 people, 7.89%
Gastrointestinal Haemorrhage (bleeding gastrointestinal tract): 2 people, 5.26%
Escherichia Infection (bacterial infection by escherichia coli): 2 people, 5.26%
Cytomegalovirus Viraemia (cytomegalo virus in blood stream): 2 people, 5.26%
Cytomegalovirus Infection: 1 person, 2.63%

* Approximation only. Some reports may have incomplete information.

Do you take Daptomycin and have Haemodynamic instability?

- Check whether Haemodynamic instability is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Daptomycin:

Daptomycin (7,879 reports)

Browse all side effects of Daptomycin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Haemodynamic instability:

Haemodynamic instability (557 drugs)

Browse all the conditions that are associated with Haemodynamic instability:

Haemodynamic instability (1,272 conditions)

Related publications that referenced our studies

Saliho?lu M, Turhan V, ?nem Y, Ulcay A, Uzun G, Ay H, "Sudden hearing loss in a patient receiving piperacillin/tazobactam and daptomycin for diabetic foot infection", Scandinavian journal of infectious diseases, 2013 Mar .
Saliho?lu M, Turhan V, ?nem Y, Ulcay A, Uzun G, Ay H, "Sudden hearing loss in a patient receiving piperacillin/tazobactam and daptomycin for diabetic foot infection", Scandinavian journal of infectious diseases, 2013 Mar .

How the study uses the data?

The study uses data from the FDA. It is based on daptomycin (the active ingredients of Daptomycin) and Daptomycin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.