Darvocet and Skin hypertrophy - a phase IV clinical study of FDA data

Summary:

Skin hypertrophy is reported as a side effect among people who take Darvocet (acetaminophen; propoxyphene hydrochloride), especially for people who are male, 60+ old, also take Magnevist, and have Nuclear magnetic resonance imaging brain.

The phase IV clinical study analyzes which people have Skin hypertrophy when taking Darvocet. It is created by eHealthMe based on reports of 11,339 people who have side effects when taking Darvocet from the FDA, and is updated regularly.

What is Darvocet?

Darvocet has active ingredients of acetaminophen; propoxyphene hydrochloride. It is often used in pain. eHealthMe is studying from 12,131 Darvocet users. Check the latest studies of Darvocet.

What is Skin hypertrophy?

Skin hypertrophy (skin cells enlarges) is found to be associated with 594 drugs and 544 conditions by eHealthMe. Check the latest studies of Skin hypertrophy.

On Jul, 08, 2026

11,339 people reported to have side effects when taking Darvocet.
Among them, 40 people (0.35%) have Skin hypertrophy.

Among these 40 people:

What is the gender of people who have Skin hypertrophy when taking Darvocet? *

female: 43.59 %
male: 56.41 %

What is the age of people who have Skin hypertrophy when taking Darvocet? *

What are other drugs people take besides Darvocet? *

What are other side effects people have besides Skin hypertrophy? *

Nephrogenic Systemic Fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease): 35 people, 87.50%
Oedema Peripheral (superficial swelling): 32 people, 80.00%
Dry Skin: 31 people, 77.50%
Skin Induration (an abnormally hard spot or area on the skin): 27 people, 67.50%
Weakness: 25 people, 62.50%
Stress And Anxiety: 23 people, 57.50%
Rashes (redness): 23 people, 57.50%
Skin Fibrosis (fibrous tissue formation on skin): 20 people, 50.00%
Emotional Distress: 19 people, 47.50%
Joint Range Of Motion Decreased (disease of joint movement): 19 people, 47.50%

What are the existing conditions these people have? *

Nuclear Magnetic Resonance Imaging Brain: 23 people, 57.50%
Nuclear Magnetic Resonance Imaging Abdominal: 7 people, 17.50%
High Blood Pressure: 7 people, 17.50%
Pulmonary Hypertension (increase in blood pressure in the lung artery): 6 people, 15.00%
Depression: 5 people, 12.50%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 5 people, 12.50%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 3 people, 7.50%
Psoriasis (immune-mediated disease that affects the skin): 3 people, 7.50%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 2 people, 5.00%
High Blood Cholesterol: 2 people, 5.00%

* Approximation only. Some reports may have incomplete information.

Do you take Darvocet and have Skin hypertrophy?

- Check whether Skin hypertrophy is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Darvocet:

Darvocet (12,131 reports)

Skin hypertrophy treatments and more:

Skin hypertrophy (4,077 reports)

How severe was Skin hypertrophy and when was it recovered:

Skin hypertrophy in Darvocet

Expand to all the drugs that have ingredients of acetaminophen; propoxyphene hydrochloride:

Skin hypertrophy and drugs with ingredients of acetaminophen; propoxyphene hydrochloride

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Darvocet:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Skin hypertrophy:

Skin hypertrophy (594 drugs)

Browse all the conditions that are associated with Skin hypertrophy:

Skin hypertrophy (544 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on acetaminophen; propoxyphene hydrochloride (the active ingredients of Darvocet) and Darvocet (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.