Darvon and Heart attack - a phase IV clinical study of FDA data

Summary:

Heart attack is reported as a side effect among people who take Darvon (propoxyphene hydrochloride), especially for people who are female, 60+ old, have been taking the drug for 10+ years also take Darvocet, and have Arthritis.

The phase IV clinical study analyzes which people have Heart attack when taking Darvon. It is created by eHealthMe based on reports of 2,707 people who have side effects when taking Darvon from the FDA, and is updated regularly.

What is Darvon?

Darvon has active ingredients of propoxyphene hydrochloride. It is often used in pain. eHealthMe is studying from 2,762 Darvon users. Check the latest studies of Darvon.

What is Heart attack?

Heart attack is found to be associated with 2,475 drugs and 3,298 conditions by eHealthMe. Check the latest studies of Heart attack.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

2,707 people reported to have side effects when taking Darvon.
Among them, 47 people (1.74%) have Heart attack.

Among these 47 people:

How long have people been on Darvon when they have Heart attack? *

What is the gender of people who have Heart attack when taking Darvon? *

female: 57.45 %
male: 42.55 %

What is the age of people who have Heart attack when taking Darvon? *

What are other drugs people take besides Darvon? *

Darvocet: 32 people, 68.09%
Propoxyphene Napsylate And Acetaminophen: 28 people, 59.57%
Vioxx: 6 people, 12.77%
Methotrexate: 4 people, 8.51%
Ambien: 4 people, 8.51%
Plavix: 3 people, 6.38%
Xanax: 3 people, 6.38%
Norvasc: 3 people, 6.38%
Remicade: 2 people, 4.26%
Protonix: 2 people, 4.26%

What are other side effects people have besides Heart attack? *

Cardiac Disorder: 19 people, 40.43%
Heart Disease: 16 people, 34.04%
Nervous System Disorder (a general class of medical conditions affecting the nervous system): 12 people, 25.53%
Movement Disorder (neurological syndromes where they may be excess of movement or a paucity of movement that is not connected to weakness): 12 people, 25.53%
Arrhythmias (irregular heartbeat): 10 people, 21.28%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 7 people, 14.89%
Myocardial Ischaemia (the blood flow through one or more of the blood vessels that lead to heart (coronary arteries) is decreased): 3 people, 6.38%
Coronary Heart Disease (narrowing or blockage of the coronary arteries): 3 people, 6.38%
Hypertensive Heart Disease: 3 people, 6.38%
Hypotension (abnormally low blood pressure): 3 people, 6.38%

What are the existing conditions these people have? *

T-Cell Lymphoma (a blood cell cancer): 2 people, 4.26%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 2 people, 4.26%
Joint Pain: 2 people, 4.26%
Insomnia (sleeplessness): 2 people, 4.26%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 2 people, 4.26%
Stress And Anxiety: 1 person, 2.13%
Neuralgia (pain in one or more nerves): 1 person, 2.13%
High Blood Pressure: 1 person, 2.13%
High Blood Cholesterol: 1 person, 2.13%
Herniated Nucleus Pulposus (Slipped Disk): 1 person, 2.13%

* Approximation only. Some reports may have incomplete information.

Do you take Darvon and have Heart attack?

- Check whether Heart attack is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Darvon:

Darvon (2,762 reports)

Heart attack treatments and more:

Heart attack (266,145 reports)

Browse all side effects of Darvon:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Heart attack:

Heart attack (2,475 drugs)

Browse all the conditions that are associated with Heart attack:

Heart attack (3,298 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on propoxyphene hydrochloride (the active ingredients of Darvon) and Darvon (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.