Darzalex and Nasal obstruction - a phase IV clinical study of FDA data

Summary:

Nasal obstruction is reported only by a few people who take Darzalex.

The phase IV clinical study analyzes which people take Darzalex and have Nasal obstruction. It is created by eHealthMe based on reports of 14,283 people who have side effects while taking Darzalex from the FDA, and is updated regularly.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.



On Sep, 20, 2022

14,283 people reported to have side effects when taking Darzalex.
Among them, 5 people (0.04%) have Nasal obstruction.


What is Darzalex?

Darzalex has active ingredients of daratumumab. eHealthMe is studying from 14,292 Darzalex users for its effectiveness, alternative drugs and more.

What is Nasal obstruction?

Nasal obstruction (blockage of nose) is found to be associated with 539 drugs and 290 conditions by eHealthMe.

Number of Darzalex and Nasal obstruction reports submitted per year:

Could Darzalex cause Nasal obstruction?

Time on Darzalex when people have Nasal obstruction *:

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Nasal obstruction when taking Darzalex *:

  • female: 100 %
  • male: 0.0 %

Age of people who have Nasal obstruction when taking Darzalex *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 100 %
  • 60+: 0.0 %

Common side effects people have besides Nasal obstruction *:

  1. Throat Tightness: 4 people, 80.00%
  2. Infusion Related Reaction: 4 people, 80.00%
  3. Sneezing: 3 people, 60.00%
  4. Rhinorrhea (watery mucus discharge from the nose): 3 people, 60.00%
  5. Chest Pain: 3 people, 60.00%
  6. Nausea (feeling of having an urge to vomit): 2 people, 40.00%
  7. Throat Irritation: 1 person, 20.00%
  8. Rashes (redness): 1 person, 20.00%
  9. Nausea And Vomiting: 1 person, 20.00%
  10. Hoarseness Or Changing Voice: 1 person, 20.00%

Common conditions people have *:

  1. Renal Amyloidosis (deposit of amyloid in kidney): 3 people, 60.00%
  2. Multiple Myeloma (cancer of the plasma cells): 2 people, 40.00%
  3. Amyloidosis (a tumour within which amyloid is produced): 1 person, 20.00%

* Approximation only. Some reports may have incomplete information.

Do you take Darzalex and have Nasal obstruction?

Check whether Nasal obstruction is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.



Related studies

How severe was Nasal obstruction and when was it recovered:

Expand to all the drugs that have ingredients of daratumumab:

Alternative drugs to, pros and cons of Darzalex:

Common Darzalex side effects:

Browse all side effects of Darzalex:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Nasal obstruction treatments and more:

COVID vaccines that are related to Nasal obstruction:

Common drugs associated with Nasal obstruction:

All the drugs that are associated with Nasal obstruction:

All the conditions that are associated with Nasal obstruction:

How the study uses the data?

The study uses data from the FDA. It is based on daratumumab (the active ingredients of Darzalex) and Darzalex (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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