Darzalex and Pericardial effusion - a phase IV clinical study of FDA data

Summary:

Pericardial effusion is reported as a side effect among people who take Darzalex (daratumumab), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Revlimid, and have Multiple myeloma.

The phase IV clinical study analyzes which people have Pericardial effusion when taking Darzalex. It is created by eHealthMe based on reports of 20,191 people who have side effects when taking Darzalex from the FDA, and is updated regularly.

What is Darzalex?

Darzalex has active ingredients of daratumumab. eHealthMe is studying from 20,206 Darzalex users. Check the latest studies of Darzalex.

What is Pericardial effusion?

Pericardial effusion (fluid around the heart) is found to be associated with 1,405 drugs and 1,462 conditions by eHealthMe. Check the latest studies of Pericardial effusion.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 26, 2026

20,191 people reported to have side effects when taking Darzalex.
Among them, 17 people (0.08%) have Pericardial effusion.

Could Darzalex cause Pericardial effusion?

Among these 17 people:

How long have people been on Darzalex when they have Pericardial effusion? *

What is the gender of people who have Pericardial effusion when taking Darzalex? *

female: 25 %
male: 75 %

What is the age of people who have Pericardial effusion when taking Darzalex? *

What are other drugs people take besides Darzalex? *

What are other side effects people have besides Pericardial effusion? *

Multiple Myeloma (cancer of the plasma cells): 7 people, 41.18%
Pleural Effusion (water on the lungs): 6 people, 35.29%
Spinal Cord Compression: 3 people, 17.65%
Cardiac Tamponade (fluid accumulates in heart covering): 2 people, 11.76%
Joint Pain: 2 people, 11.76%
Thrombocytopenia (decrease of platelets in blood): 2 people, 11.76%
Pulmonary Oedema (fluid accumulation in the lungs): 2 people, 11.76%
Cardiac Arrest: 2 people, 11.76%
Chest Pain: 2 people, 11.76%
Hypotension (abnormally low blood pressure): 2 people, 11.76%

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 13 people, 76.47%
Acute Lymphocytic Leukemia (All) (cancer of the white blood cells characterized by excess lymphoblasts): 2 people, 11.76%
Monoclonal Gammopathy: 1 person, 5.88%
Constipation: 1 person, 5.88%

* Approximation only. Some reports may have incomplete information.

Do you take Darzalex and have Pericardial effusion?

- Check whether Pericardial effusion is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Darzalex:

Darzalex (20,206 reports)

Browse all side effects of Darzalex:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Pericardial effusion:

Pericardial effusion (1,405 drugs)

Browse all the conditions that are associated with Pericardial effusion:

Pericardial effusion (1,462 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on daratumumab (the active ingredients of Darzalex) and Darzalex (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.