Ddavp and Death - a phase IV clinical study of FDA data

Summary:

Death is reported as a side effect among people who take Ddavp (desmopressin acetate), especially for people who are female, 60+ old, have been taking the drug for 10+ years also take Trasylol, and have Growth hormone deficiency.

The study is created by eHealthMe based on reports of 2,531 people who have side effects when taking Ddavp from the FDA, and is updated regularly.

What is Ddavp?

Ddavp has active ingredients of desmopressin acetate. It is often used in diabetes insipidus. eHealthMe is studying from 2,614 Ddavp users. Check the latest studies of Ddavp.



On Jul, 10, 2026

2,531 people reported to have side effects when taking Ddavp.
Among them, 45 people (1.78%) died.

Could Ddavp cause Death?

Among these 45 people:

How long have people been on Ddavp when they died? *

  • < 1 month: 25 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 75 %

What is the gender of people who died when taking Ddavp? *

  • female: 75.56 %
  • male: 24.44 %

What is the age of people who died when taking Ddavp? *

  • 0-1: 0.0 %
  • 2-9: 10.26 %
  • 10-19: 7.69 %
  • 20-29: 7.69 %
  • 30-39: 7.69 %
  • 40-49: 10.26 %
  • 50-59: 10.26 %
  • 60+: 46.15 %

What are other drugs people take besides Ddavp? *

  1. Synthroid: 9 people, 20.00%
  2. Trasylol: 9 people, 20.00%
  3. Hydrocortisone: 8 people, 17.78%
  4. Protamine Sulfate: 7 people, 15.56%
  5. Lasix: 7 people, 15.56%
  6. Lantus: 7 people, 15.56%
  7. Levothyroxine Sodium: 6 people, 13.33%
  8. Norditropin: 5 people, 11.11%
  9. Vancomycin: 5 people, 11.11%
  10. Aspirin: 5 people, 11.11%

What are other side effects people have before they died? *

  1. Pain: 10 people, 22.22%
  2. Acute Kidney Failure: 9 people, 20.00%
  3. Injury: 9 people, 20.00%
  4. Anhedonia (inability to experience pleasure from activities usually found enjoyable): 9 people, 20.00%
  5. Stress And Anxiety: 8 people, 17.78%
  6. Fear: 8 people, 17.78%
  7. Multi-Organ Failure (multisystem organ failure): 7 people, 15.56%
  8. Emotional Distress: 7 people, 15.56%
  9. Renal Injury (kidney injury): 7 people, 15.56%
  10. Renal Impairment (severely reduced kidney function): 6 people, 13.33%

What are the existing conditions these people have? *

  1. Growth Hormone Deficiency: 9 people, 20.00%
  2. Diabetes: 8 people, 17.78%
  3. Hypopituitarism (diminished hormone secretion by the pituitary gland, causing dwarfism in children and premature aging in adults): 6 people, 13.33%
  4. Hyperlipidaemia (presence of excess lipids in the blood): 4 people, 8.89%
  5. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 4 people, 8.89%
  6. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 3 people, 6.67%
  7. Adrenal Insufficiency (a condition in which the adrenal glands do not produce adequate amounts of steroids): 3 people, 6.67%
  8. Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 3 people, 6.67%
  9. Infantile Spasms: 2 people, 4.44%
  10. Pain: 2 people, 4.44%

* Approximation only. Some reports may have incomplete information.



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Ddavp:

Expand to all the drugs that have ingredients of desmopressin acetate:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Ddavp:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Death:

Browse all the conditions that are associated with Death:

  • Death (3,686 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on desmopressin acetate (the active ingredients of Ddavp) and Ddavp (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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