Definity and Heart attack - a phase IV clinical study of FDA data

Summary:

Heart attack is reported as a side effect among people who take Definity (perflutren), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Lasix, and have Pain.

The phase IV clinical study analyzes which people have Heart attack when taking Definity. It is created by eHealthMe based on reports of 4,852 people who have side effects when taking Definity from the FDA, and is updated regularly.

What is Definity?

Definity has active ingredients of perflutren. eHealthMe is studying from 4,853 Definity users. Check the latest studies of Definity.

What is Heart attack?

Heart attack is found to be associated with 2,536 drugs and 3,272 conditions by eHealthMe. Check the latest studies of Heart attack.

On Jan, 20, 2026

4,852 people reported to have side effects when taking Definity.
Among them, 15 people (0.31%) have Heart attack.

Among these 15 people:

How long have people been on Definity when they have Heart attack? *

What is the gender of people who have Heart attack when taking Definity? *

female: 14.29 %
male: 85.71 %

What is the age of people who have Heart attack when taking Definity? *

What are other drugs people take besides Definity? *

What are other side effects people have besides Heart attack? *

Hypotension (abnormally low blood pressure): 6 people, 40.00%
Chest Pain: 3 people, 20.00%
Rashes (redness): 3 people, 20.00%
Loss Of Consciousness: 2 people, 13.33%
Ventricular Fibrillation (abnormally irregular heart rhythm): 2 people, 13.33%
Hyperhidrosis (abnormally increased sweating): 2 people, 13.33%
Coronary Artery Occlusion (complete obstruction of blood flow in a coronary artery): 2 people, 13.33%
Dyspnea (difficult or laboured breathing): 2 people, 13.33%
Cardiac Procedure Complication: 1 person, 6.67%
Cardio-Respiratory Arrest (sudden dysfunction of heart and lungs): 1 person, 6.67%

What are the existing conditions these people have? *

Pain: 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

Do you take Definity and have Heart attack?

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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Definity:

Definity (4,853 reports)

Heart attack treatments and more:

Heart attack (266,139 reports)

Browse all side effects of Definity:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Heart attack:

Heart attack (2,536 drugs)

Browse all the conditions that are associated with Heart attack:

Heart attack (3,272 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on perflutren (the active ingredients of Definity) and Definity (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.