Definity and Wheezing aggravated - a phase IV clinical study of FDA data

Summary:

Wheezing aggravated is reported as a side effect among people who take Definity (perflutren), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Lasix, and have High blood pressure.

The phase IV clinical study analyzes which people have Wheezing aggravated when taking Definity. It is created by eHealthMe based on reports of 4,852 people who have side effects when taking Definity from the FDA, and is updated regularly.

What is Definity?

Definity has active ingredients of perflutren. eHealthMe is studying from 4,853 Definity users. Check the latest studies of Definity.

What is Wheezing aggravated?

Wheezing aggravated (a high-pitched whistling sound made while you breath) is found to be associated with 1,327 drugs and 500 conditions by eHealthMe. Check the latest studies of Wheezing aggravated.

On Jul, 14, 2026

4,852 people reported to have side effects when taking Definity.
Among them, 40 people (0.82%) have Wheezing aggravated.

Could Definity cause Wheezing aggravated?

Among these 40 people:

How long have people been on Definity when they have Wheezing aggravated? *

What is the gender of people who have Wheezing aggravated when taking Definity? *

female: 59.46 %
male: 40.54 %

What is the age of people who have Wheezing aggravated when taking Definity? *

What are other drugs people take besides Definity? *

What are other side effects people have besides Wheezing aggravated? *

Dyspnea (difficult or laboured breathing): 26 people, 65.00%
Itching: 8 people, 20.00%
Urticaria (rash of round, red welts on the skin that itch intensely): 8 people, 20.00%
Back Pain: 8 people, 20.00%
Chest Pain: 6 people, 15.00%
Rashes (redness): 6 people, 15.00%
Hypotension (abnormally low blood pressure): 6 people, 15.00%
Dizziness: 6 people, 15.00%
Oxygen Saturation Decreased: 5 people, 12.50%
Cough: 4 people, 10.00%

What are the existing conditions these people have? *

High Blood Pressure: 2 people, 5.00%
Quit Smoking: 1 person, 2.50%
Hyperkalemia (damage to or disease of the kidney): 1 person, 2.50%
Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 1 person, 2.50%
Chest Pain: 1 person, 2.50%
Cardiac Failure Congestive: 1 person, 2.50%
Back Pain: 1 person, 2.50%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 1 person, 2.50%
Asthma: 1 person, 2.50%

* Approximation only. Some reports may have incomplete information.

Do you take Definity and have Wheezing aggravated?

- Check whether Wheezing aggravated is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Definity:

Definity (4,853 reports)

Browse all side effects of Definity:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Wheezing aggravated:

Wheezing aggravated (1,327 drugs)

Browse all the conditions that are associated with Wheezing aggravated:

Wheezing aggravated (500 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on perflutren (the active ingredients of Definity) and Definity (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.