Delsym and Cannot sleep - a phase IV clinical study of FDA data

Summary:

Cannot sleep is reported as a side effect among people who take Delsym (dextromethorphan polistirex), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Vitamin D3, and have Nasopharyngitis.

The phase IV clinical study analyzes which people have Cannot sleep when taking Delsym. It is created by eHealthMe based on reports of 4,675 people who have side effects when taking Delsym from the FDA, and is updated regularly.

What is Delsym?

Delsym has active ingredients of dextromethorphan polistirex. It is often used in cough. eHealthMe is studying from 5,033 Delsym users. Check the latest studies of Delsym.

What is Cannot sleep?

Cannot sleep is found to be associated with 4,512 drugs and 5,373 conditions by eHealthMe. Check the latest studies of Cannot sleep.

On Feb, 04, 2026

4,675 people reported to have side effects when taking Delsym.
Among them, 166 people (3.55%) have Cannot sleep.

Among these 166 people:

* Approximation only. Some reports may have incomplete information.

Do you take Delsym and have Cannot sleep?

- Check whether Cannot sleep is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Delsym:

Delsym (5,033 reports)

Cannot sleep treatments and more:

Cannot sleep (438,064 reports)

How severe was Cannot sleep and when was it recovered:

Cannot sleep in Delsym

Expand to all the drugs that have ingredients of dextromethorphan polistirex:

Cannot sleep and drugs with ingredients of dextromethorphan polistirex (189 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Delsym:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Cannot sleep:

Cannot sleep (4,512 drugs)

Browse all the conditions that are associated with Cannot sleep:

Cannot sleep (5,373 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on dextromethorphan polistirex (the active ingredients of Delsym) and Delsym (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.