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Depakene and Eosinophil count increased - a phase IV clinical study of FDA data

Summary:

Eosinophil count increased is reported as a side effect among people who take Depakene (valproic acid), especially for people who are male, 40-49 old, have been taking the drug for 1 - 6 months also take Lamictal, and have Schizophrenia.

The phase IV clinical study analyzes which people have Eosinophil count increased when taking Depakene. It is created by eHealthMe based on reports of 14,611 people who have side effects when taking Depakene from the FDA, and is updated regularly.

What is Depakene?

Depakene has active ingredients of valproic acid. It is often used in epilepsy. eHealthMe is studying from 14,776 Depakene users. Check the latest studies of Depakene.

What is Eosinophil count increased?

Eosinophil count increased is found to be associated with 768 drugs and 1,129 conditions by eHealthMe. Check the latest studies of Eosinophil count increased.

On Jul, 11, 2026

14,611 people reported to have side effects when taking Depakene.
Among them, 83 people (0.57%) have Eosinophil count increased.

Could Depakene cause Eosinophil count increased?

Among these 83 people:

How long have people been on Depakene when they have Eosinophil count increased? *

  • < 1 month: 25 %
  • 1 - 6 months: 35 %
  • 6 - 12 months: 15 %
  • 1 - 2 years: 15 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 5 %
  • 10+ years: 5 %

What is the gender of people who have Eosinophil count increased when taking Depakene? *

  • female: 28.21 %
  • male: 71.79 %

What is the age of people who have Eosinophil count increased when taking Depakene? *

  • 0-1: 1.32 %
  • 2-9: 2.63 %
  • 10-19: 6.58 %
  • 20-29: 17.11 %
  • 30-39: 9.21 %
  • 40-49: 32.89 %
  • 50-59: 13.16 %
  • 60+: 17.11 %

What are other drugs people take besides Depakene? *

  1. Lamictal: 31 people, 37.35%
  2. Tegretol: 23 people, 27.71%
  3. Clozaril: 12 people, 14.46%
  4. Polaramine: 9 people, 10.84%
  5. Risperdal: 9 people, 10.84%
  6. Prednisolone: 7 people, 8.43%
  7. Tamiflu: 7 people, 8.43%
  8. Zyprexa: 6 people, 7.23%
  9. Akineton: 5 people, 6.02%
  10. Voltaren: 5 people, 6.02%

What are other side effects people have besides Eosinophil count increased? *

  1. Fever: 47 people, 56.63%
  2. Drug Eruption (adverse drug reaction of the skin): 33 people, 39.76%
  3. White Blood Cell Count Increased: 29 people, 34.94%
  4. Rashes (redness): 26 people, 31.33%
  5. Aspartate Aminotransferase Increased: 22 people, 26.51%
  6. Gamma-Glutamyltransferase Increased: 20 people, 24.10%
  7. Lymph Follicular Hypertrophy (an increase in the size of the lymph node follicles): 19 people, 22.89%
  8. Blood Lactate Dehydrogenase Increased: 18 people, 21.69%
  9. C-Reactive Protein Increased: 18 people, 21.69%
  10. Alanine Aminotransferase Increased: 17 people, 20.48%

What are the existing conditions these people have? *

  1. Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 9 people, 10.84%
  2. Depression: 7 people, 8.43%
  3. The Flu (the flu is caused by an influenza virus): 7 people, 8.43%
  4. Headache (pain in head): 7 people, 8.43%
  5. Emphysema (chronic respiratory disease - over inflation of the air sacs (alveoli) in the lungs): 5 people, 6.02%
  6. Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 5 people, 6.02%
  7. Schizophrenia, Paranoid Type (delusions and auditory hallucinations but relatively normal intellectual functioning and expression of affect): 5 people, 6.02%
  8. Temporal Lobe Epilepsy (a term that refers to a condition where seizures are generated in the portion of the brain called the temporal lobe): 5 people, 6.02%
  9. Pain In Jaw: 5 people, 6.02%
  10. Neck Pain: 5 people, 6.02%

* Approximation only. Some reports may have incomplete information.

Do you take Depakene and have Eosinophil count increased?

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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Depakene:

Eosinophil count increased treatments and more:

How severe was Eosinophil count increased and when was it recovered:

Expand to all the drugs that have ingredients of valproic acid:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Depakene:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Eosinophil count increased:

Browse all the conditions that are associated with Eosinophil count increased:

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on valproic acid (the active ingredients of Depakene) and Depakene (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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