Depakote er and Drooling - a phase IV clinical study of FDA data

Summary:

Drooling is reported as a side effect among people who take Depakote er (divalproex sodium), especially for people who are male, 10-19 old, have been taking the drug for < 1 month also take Invega Sustenna, and have Pain.

The phase IV clinical study analyzes which people have Drooling when taking Depakote er. It is created by eHealthMe based on reports of 5,099 people who have side effects when taking Depakote er from the FDA, and is updated regularly.

What is Depakote er?

Depakote er has active ingredients of divalproex sodium. It is often used in bipolar disorder. eHealthMe is studying from 6,042 Depakote er users. Check the latest studies of Depakote er.

What is Drooling?

Drooling (drop saliva uncontrollably from the mouth) is found to be associated with 497 drugs and 941 conditions by eHealthMe. Check the latest studies of Drooling.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 01, 2026

5,099 people reported to have side effects when taking Depakote er.
Among them, 21 people (0.41%) have Drooling.

Among these 21 people:

How long have people been on Depakote er when they have Drooling? *

What is the gender of people who have Drooling when taking Depakote er? *

female: 50 %
male: 50 %

What is the age of people who have Drooling when taking Depakote er? *

What are other drugs people take besides Depakote er? *

What are other side effects people have besides Drooling? *

Fatigue (feeling of tiredness): 7 people, 33.33%
Agitation (state of anxiety or nervous excitement): 4 people, 19.05%
Tremor (trembling or shaking movements in one or more parts of your body): 4 people, 19.05%
Swallowing Difficulty: 3 people, 14.29%
Pain: 2 people, 9.52%
Drowsiness: 2 people, 9.52%
Oral Pain: 2 people, 9.52%
Drug Hypersensitivity: 2 people, 9.52%
Drug Ineffective: 2 people, 9.52%
Eating Disorder: 2 people, 9.52%

What are the existing conditions these people have? *

Tardive Dyskinesia (a disorder that involves involuntary movements): 3 people, 14.29%
Stress And Anxiety: 3 people, 14.29%
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 3 people, 14.29%
Pain: 3 people, 14.29%
Blood Pressure Abnormal: 2 people, 9.52%
Fungal Infection: 2 people, 9.52%
Diabetes: 2 people, 9.52%
High Blood Pressure: 2 people, 9.52%
Swelling: 2 people, 9.52%
Hypersensitivity: 2 people, 9.52%

* Approximation only. Some reports may have incomplete information.

Do you take Depakote er and have Drooling?

- Check whether Drooling is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Depakote er:

Depakote er (6,042 reports)

Drooling treatments and more:

Drooling (8,115 reports)

Browse all side effects of Depakote er:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Drooling:

Drooling (497 drugs)

Browse all the conditions that are associated with Drooling:

Drooling (941 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on divalproex sodium (the active ingredients of Depakote er) and Depakote er (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.