Depakote er and Suicide attempt - a phase IV clinical study of FDA data

Summary:

Suicide attempt is reported as a side effect among people who take Depakote er (divalproex sodium), especially for people who are male, 20-29 old, have been taking the drug for < 1 month also take Lexapro, and have Attention deficit hyperactivity disorder.

The phase IV clinical study analyzes which people have Suicide attempt when taking Depakote er. It is created by eHealthMe based on reports of 5,099 people who have side effects when taking Depakote er from the FDA, and is updated regularly.

What is Depakote er?

Depakote er has active ingredients of divalproex sodium. It is often used in bipolar disorder. eHealthMe is studying from 6,042 Depakote er users. Check the latest studies of Depakote er.

What is Suicide attempt?

Suicide attempt is found to be associated with 1,379 drugs and 1,492 conditions by eHealthMe. Check the latest studies of Suicide attempt.

On Jul, 02, 2026

5,099 people reported to have side effects when taking Depakote er.
Among them, 46 people (0.9%) have Suicide attempt.

Could Depakote er cause Suicide attempt?

Among these 46 people:

How long have people been on Depakote er when they have Suicide attempt? *

What is the gender of people who have Suicide attempt when taking Depakote er? *

female: 42.22 %
male: 57.78 %

What is the age of people who have Suicide attempt when taking Depakote er? *

What are other drugs people take besides Depakote er? *

What are other side effects people have besides Suicide attempt? *

Depression: 19 people, 41.30%
Agitation (state of anxiety or nervous excitement): 13 people, 28.26%
Suicidal Ideation: 12 people, 26.09%
Rashes (redness): 11 people, 23.91%
Panic Disorder: 9 people, 19.57%
Stress And Anxiety: 9 people, 19.57%
Head Injury: 8 people, 17.39%
Burns Third Degree: 8 people, 17.39%
Psychotic Disorder: 8 people, 17.39%
Headache (pain in head): 8 people, 17.39%

What are the existing conditions these people have? *

Attention Deficit Hyperactivity Disorder (a chronic condition including attention difficulty, hyperactivity, and impulsiveness): 7 people, 15.22%
Stress And Anxiety: 6 people, 13.04%
Depression: 5 people, 10.87%
Asthma: 4 people, 8.70%
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure): 4 people, 8.70%
Agitation (state of anxiety or nervous excitement): 2 people, 4.35%
Sleep Disorder: 2 people, 4.35%
Overdose: 2 people, 4.35%
Mental Disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability): 2 people, 4.35%
Major Depression (a mood state that goes well beyond temporarily feeling sad or blue. it is a serious medical illness that affects one's thoughts, feelings): 2 people, 4.35%

* Approximation only. Some reports may have incomplete information.

Do you take Depakote er and have Suicide attempt?

- Check whether Suicide attempt is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Depakote er:

Depakote er (6,042 reports)

Suicide attempt treatments and more:

Suicide attempt (81,434 reports)

Browse all side effects of Depakote er:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Suicide attempt:

Suicide attempt (1,379 drugs)

Browse all the conditions that are associated with Suicide attempt:

Suicide attempt (1,492 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on divalproex sodium (the active ingredients of Depakote er) and Depakote er (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.