Depakote and Haemoglobin increased - a phase IV clinical study of FDA data

Summary:

Haemoglobin increased is reported as a side effect among people who take Depakote (divalproex sodium), especially for people who are female, 40-49 old, have been taking the drug for 6 - 12 months also take Zyrtec, and have Pain.

The phase IV clinical study analyzes which people have Haemoglobin increased when taking Depakote. It is created by eHealthMe based on reports of 52,619 people who have side effects when taking Depakote from the FDA, and is updated regularly.

What is Depakote?

Depakote has active ingredients of divalproex sodium. It is often used in bipolar disorder. eHealthMe is studying from 55,581 Depakote users. Check the latest studies of Depakote.

What is Haemoglobin increased?

Haemoglobin increased is found to be associated with 480 drugs and 537 conditions by eHealthMe. Check the latest studies of Haemoglobin increased.

On Jul, 16, 2026

52,619 people reported to have side effects when taking Depakote.
Among them, 23 people (0.04%) have Haemoglobin increased.

Could Depakote cause Haemoglobin increased?

Among these 23 people:

How long have people been on Depakote when they have Haemoglobin increased? *

What is the gender of people who have Haemoglobin increased when taking Depakote? *

female: 52.38 %
male: 47.62 %

What is the age of people who have Haemoglobin increased when taking Depakote? *

What are other drugs people take besides Depakote? *

What are other side effects people have besides Haemoglobin increased? *

Haematocrit Increased: 11 people, 47.83%
High Blood Cholesterol: 6 people, 26.09%
Red Blood Cell Count Increased: 5 people, 21.74%
Pancreatitis Haemorrhagic (inflammation of pancreas with bleeding): 4 people, 17.39%
Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 4 people, 17.39%
Pleural Effusion (water on the lungs): 4 people, 17.39%
Type 2 Diabetes: 4 people, 17.39%
Blood In Stool: 4 people, 17.39%
Hepatic Failure (liver failure): 4 people, 17.39%
Dehydration (dryness resulting from the removal of water): 4 people, 17.39%

What are the existing conditions these people have? *

Pain: 3 people, 13.04%
Affective Disorder (mental disorder): 2 people, 8.70%
Polycythaemia Vera (blood disorder in which the bone marrow makes too many red blood cells): 2 people, 8.70%
Agitation (state of anxiety or nervous excitement): 2 people, 8.70%
High Blood Pressure: 2 people, 8.70%
Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 2 people, 8.70%
Depression: 2 people, 8.70%
Diabetes: 1 person, 4.35%
Aggression: 1 person, 4.35%
Anaemia (lack of blood): 1 person, 4.35%

* Approximation only. Some reports may have incomplete information.

Do you take Depakote and have Haemoglobin increased?

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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Depakote:

Depakote (55,581 reports)

Browse all side effects of Depakote:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Haemoglobin increased:

Haemoglobin increased (480 drugs)

Browse all the conditions that are associated with Haemoglobin increased:

Haemoglobin increased (537 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on divalproex sodium (the active ingredients of Depakote) and Depakote (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.