Depakote and Panic attack - a phase IV clinical study of FDA data

Summary:

Panic attack is reported as a side effect among people who take Depakote (divalproex sodium), especially for people who are female, 50-59 old, have been taking the drug for 1 - 6 months also take Seroquel, and have Depression.

The phase IV clinical study analyzes which people have Panic attack when taking Depakote. It is created by eHealthMe based on reports of 52,619 people who have side effects when taking Depakote from the FDA, and is updated regularly.

What is Depakote?

Depakote has active ingredients of divalproex sodium. It is often used in bipolar disorder. eHealthMe is studying from 55,576 Depakote users. Check the latest studies of Depakote.

What is Panic attack?

Panic attack is found to be associated with 2,553 drugs and 2,065 conditions by eHealthMe. Check the latest studies of Panic attack.



On Sep, 15, 2025

52,619 people reported to have side effects when taking Depakote.
Among them, 371 people (0.71%) have Panic attack.

Could Depakote cause Panic attack?

Among these 371 people:

How long have people been on Depakote when they have Panic attack? *

  • < 1 month: 10.0 %
  • 1 - 6 months: 52.5 %
  • 6 - 12 months: 15.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 5.0 %
  • 5 - 10 years: 7.5 %
  • 10+ years: 10.0 %

What is the gender of people who have Panic attack when taking Depakote? *

  • female: 62.92 %
  • male: 37.08 %

What is the age of people who have Panic attack when taking Depakote? *

  • 0-1: 0.0 %
  • 2-9: 0.8 %
  • 10-19: 7.17 %
  • 20-29: 7.97 %
  • 30-39: 22.71 %
  • 40-49: 24.7 %
  • 50-59: 25.5 %
  • 60+: 11.16 %

What are other drugs people take besides Depakote? *

  1. Seroquel: 79 people, 21.29%
  2. Xanax: 53 people, 14.29%
  3. Klonopin: 50 people, 13.48%
  4. Zoloft: 50 people, 13.48%
  5. Risperdal: 46 people, 12.40%
  6. Prozac: 46 people, 12.40%
  7. Paxil: 44 people, 11.86%
  8. Ambien: 42 people, 11.32%
  9. Abilify: 42 people, 11.32%
  10. Zyprexa: 41 people, 11.05%

What are other side effects people have besides Panic attack? *

  1. Stress And Anxiety: 151 people, 40.70%
  2. Depression: 99 people, 26.68%
  3. Insomnia (sleeplessness): 64 people, 17.25%
  4. Headache (pain in head): 64 people, 17.25%
  5. Drowsiness: 64 people, 17.25%
  6. Weight Increased: 61 people, 16.44%
  7. High Blood Pressure: 54 people, 14.56%
  8. Drug Ineffective: 52 people, 14.02%
  9. Dyspnea (difficult or laboured breathing): 51 people, 13.75%
  10. Suicidal Ideation: 50 people, 13.48%

What are the existing conditions these people have? *

  1. Depression: 57 people, 15.36%
  2. Stress And Anxiety: 42 people, 11.32%
  3. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 35 people, 9.43%
  4. Pain: 34 people, 9.16%
  5. Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 25 people, 6.74%
  6. Headache (pain in head): 20 people, 5.39%
  7. High Blood Pressure: 19 people, 5.12%
  8. Insomnia (sleeplessness): 19 people, 5.12%
  9. Sleep Disorder: 17 people, 4.58%
  10. Seizures (abnormal excessive or synchronous neuronal activity in the brain): 17 people, 4.58%

* Approximation only. Some reports may have incomplete information.

Do you take Depakote and have Panic attack?

- Check whether Panic attack is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Depakote:

Panic attack treatments and more:

How severe was Panic attack and when was it recovered:

Expand to all the drugs that have ingredients of divalproex sodium:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Common Depakote side effects:

Browse all side effects of Depakote:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Common drugs associated with Panic attack:

Browse all the drugs that are associated with Panic attack:

Common conditions associated with Panic attack:

Browse all the conditions that are associated with Panic attack:

Drugs similar to Depakote and Panic attack :


How the study uses the data?

The study uses data from the FDA. It is based on divalproex sodium (the active ingredients of Depakote) and Depakote (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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