Depakote and Tremor - a phase IV clinical study of FDA data
Summary:
Tremor is found among people who take Depakote, especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months.
The phase IV clinical study analyzes which people take Depakote and have Tremor. It is created by eHealthMe based on reports of 51,553 people who have side effects when taking Depakote from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.
Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.
51,553 people reported to have side effects when taking Depakote.
Among them, 2,246 people (4.36%) have Tremor.
What is Depakote?
Depakote has active ingredients of divalproex sodium. It is often used in bipolar disorder. eHealthMe is studying from 52,797 Depakote users for its effectiveness, alternative drugs and more.
What is Tremor?
Tremor (trembling or shaking movements in one or more parts of your body) is found to be associated with 3,958 drugs and 3,687 conditions by eHealthMe.
Number of Depakote and Tremor reports submitted per year:

Time on Depakote when people have Tremor *:
Gender of people who have Tremor when taking Depakote*:
Age of people who have Tremor when taking Depakote *:
Common drugs people take besides Depakote *:
Common side effects people have besides Tremor *:
Common conditions people have *:
* Approximation only. Some reports may have incomplete information.
Do you take Depakote and have Tremor?
Check whether Tremor is associated with a drug or a conditionHow to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Related studies
How severe was Tremor and when was it recovered:
Expand to all the drugs that have ingredients of divalproex sodium:
- Tremor and drugs with ingredients of divalproex sodium (2,230 reports)
Alternative drugs to, pros and cons of Depakote:
- Depakote (52,797 reports)
Common Depakote side effects:
- Weight increased: 2,766 reports
- Fatigue (feeling of tiredness): 2,716 reports
- Drug ineffective: 2,665 reports
- Stress and anxiety: 2,513 reports
- Pain: 2,310 reports
- Tremor (trembling or shaking movements in one or more parts of your body): 2,246 reports
- Drowsiness: 2,191 reports
Browse all side effects of Depakote:
a b c d e f g h i j k l m n o p q r s t u v w x y zTremor treatments and more:
- Tremor (174,311 reports)
COVID vaccines that are related to Tremor:
- Tremor in Moderna COVID Vaccine
- Tremor in Pfizer BioNTech Covid Vaccine
- Tremor in Johnson and Johnson Covid Vaccine
Common drugs associated with Tremor:
- Aspirin: 6,839 reports
- Prednisone: 5,784 reports
- Lyrica: 5,266 reports
- Gabapentin: 5,171 reports
- Omeprazole: 5,033 reports
- Cymbalta: 4,860 reports
- Metformin: 4,761 reports
- Synthroid: 4,070 reports
- Paxil: 3,848 reports
- Xanax: 3,815 reports
All the drugs that are associated with Tremor:
- Tremor (3,958 drugs)
Common conditions associated with Tremor:
- Multiple sclerosis: 12,774 reports
- Depression: 11,268 reports
- Pain: 6,908 reports
- High blood pressure: 6,473 reports
- Parkinson's disease: 5,851 reports
All the conditions that are associated with Tremor:
- Tremor (3,687 conditions)
How the study uses the data?
The study uses data from the FDA. It is based on divalproex sodium (the active ingredients of Depakote) and Depakote (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
Recent studies on eHealthMe:
- Etodolac and Loss Of Libido - 2 seconds ago
- Microgestin 1.5/30 and Zide drug interaction - 8 seconds ago
- Irritability and drugs of ingredients of esomeprazole magnesium - 11 seconds ago
- Pamidronate Disodium and Linezolid drug interaction - 12 seconds ago
- Sodium Bicarbonate and Subarachnoid Haemorrhage - 19 seconds ago
- Levemir Flextouch and Hydroxyzine drug interaction - 20 seconds ago
- Pregabalin and Theophylline drug interaction - 21 seconds ago
- Digoxin vs. Jantoven - 21 seconds ago
- Escitalopram and Application Site Pruritus - 37 seconds ago
- Aspirin and Central Nervous System Haemorrhage - 45 seconds ago