Depakote and Tremor - a phase IV clinical study of FDA data

Summary:

Tremor is reported as a side effect among people who take Depakote (divalproex sodium), especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months also take Seroquel, and have Depression.

The phase IV clinical study analyzes which people have Tremor when taking Depakote. It is created by eHealthMe based on reports of 52,619 people who have side effects when taking Depakote from the FDA, and is updated regularly.

What is Depakote?

Depakote has active ingredients of divalproex sodium. It is often used in bipolar disorder. eHealthMe is studying from 55,581 Depakote users. Check the latest studies of Depakote.

What is Tremor?

Tremor (trembling or shaking movements in one or more parts of your body) is found to be associated with 2,643 drugs and 3,727 conditions by eHealthMe. Check the latest studies of Tremor.

On Apr, 16, 2026

52,619 people reported to have side effects when taking Depakote.
Among them, 2,284 people (4.34%) have Tremor.

Among these 2,284 people:

* Approximation only. Some reports may have incomplete information.

Do you take Depakote and have Tremor?

- Check whether Tremor is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Depakote:

Depakote (55,581 reports)

Tremor treatments and more:

Tremor (195,267 reports)

How severe was Tremor and when was it recovered:

Tremor in Depakote

Expand to all the drugs that have ingredients of divalproex sodium:

Tremor and drugs with ingredients of divalproex sodium (2,686 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Depakote:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Tremor:

Tremor (2,643 drugs)

Browse all the conditions that are associated with Tremor:

Tremor (3,727 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on divalproex sodium (the active ingredients of Depakote) and Depakote (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.