Depo-medrol and Gingival bleeding - a phase IV clinical study of FDA data

Summary:

Gingival bleeding is reported as a side effect among people who take Depo-medrol (methylprednisolone acetate), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Lasix, and have Pain.

The phase IV clinical study analyzes which people have Gingival bleeding when taking Depo-medrol. It is created by eHealthMe based on reports of 5,847 people who have side effects when taking Depo-medrol from the FDA, and is updated regularly.

What is Depo-medrol?

Depo-medrol has active ingredients of methylprednisolone acetate. It is often used in birth control. eHealthMe is studying from 5,933 Depo-medrol users. Check the latest studies of Depo-medrol.

What is Gingival bleeding?

Gingival bleeding (bleeding gums) is found to be associated with 1,031 drugs and 1,082 conditions by eHealthMe. Check the latest studies of Gingival bleeding.

On Jul, 07, 2026

5,847 people reported to have side effects when taking Depo-medrol.
Among them, 17 people (0.29%) have Gingival bleeding.

Could Depo-medrol cause Gingival bleeding?

Among these 17 people:

How long have people been on Depo-medrol when they have Gingival bleeding? *

What is the gender of people who have Gingival bleeding when taking Depo-medrol? *

female: 100 %
male: 0.0 %

What is the age of people who have Gingival bleeding when taking Depo-medrol? *

What are other drugs people take besides Depo-medrol? *

What are other side effects people have besides Gingival bleeding? *

Impaired Healing: 14 people, 82.35%
Pain: 11 people, 64.71%
Skin Disorder (skin disease): 10 people, 58.82%
Muscle Spasms (muscle contraction): 10 people, 58.82%
Cough: 10 people, 58.82%
Urinary Tract Infection: 9 people, 52.94%
Stress And Anxiety: 9 people, 52.94%
Headache (pain in head): 9 people, 52.94%
Insomnia (sleeplessness): 8 people, 47.06%
Gingival Erosion (gum ulcer): 8 people, 47.06%

What are the existing conditions these people have? *

Pain: 8 people, 47.06%
Back Pain: 3 people, 17.65%
Osteoporosis (bones weak and more likely to break): 2 people, 11.76%
Systemic Lupus Erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 1 person, 5.88%
Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 1 person, 5.88%
Myelodysplastic Syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged): 1 person, 5.88%
Insomnia (sleeplessness): 1 person, 5.88%
Gastroenteritis (inflammation of stomach and intestine): 1 person, 5.88%
Bipolar I Disorder (mood disorder that is characterized by at least one manic or mixed episode): 1 person, 5.88%

* Approximation only. Some reports may have incomplete information.

Do you take Depo-medrol and have Gingival bleeding?

- Check whether Gingival bleeding is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Depo-medrol:

Depo-medrol (5,933 reports)

Browse all side effects of Depo-medrol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Gingival bleeding:

Gingival bleeding (1,031 drugs)

Browse all the conditions that are associated with Gingival bleeding:

Gingival bleeding (1,082 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on methylprednisolone acetate (the active ingredients of Depo-medrol) and Depo-medrol (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.