Depo-medrol and Hot flush - a phase IV clinical study of FDA data

Summary:

Hot flush is reported as a side effect among people who take Depo-medrol (methylprednisolone acetate), especially for people who are 50-59 old, have been taking the drug for < 1 month also take Fish Oil, and have Metastases to bone.

The phase IV clinical study analyzes which people have Hot flush when taking Depo-medrol. It is created by eHealthMe based on reports of 5,847 people who have side effects when taking Depo-medrol from the FDA, and is updated regularly.

What is Depo-medrol?

Depo-medrol has active ingredients of methylprednisolone acetate. It is often used in birth control. eHealthMe is studying from 5,933 Depo-medrol users. Check the latest studies of Depo-medrol.

What is Hot flush?

Hot flush (sudden feelings of heat) is found to be associated with 1,769 drugs and 2,342 conditions by eHealthMe. Check the latest studies of Hot flush.



On Jul, 12, 2026

5,847 people reported to have side effects when taking Depo-medrol.
Among them, 30 people (0.51%) have Hot flush.

Could Depo-medrol cause Hot flush?

Among these 30 people:

How long have people been on Depo-medrol when they have Hot flush? *

  • < 1 month: 66.67 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 33.33 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the age of people who have Hot flush when taking Depo-medrol? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 8.7 %
  • 40-49: 8.7 %
  • 50-59: 43.48 %
  • 60+: 39.13 %

What are other drugs people take besides Depo-medrol? *

  1. Methocarbamol: 6 people, 20.00%
  2. Taxol: 6 people, 20.00%
  3. Zometa: 6 people, 20.00%
  4. Lupron: 6 people, 20.00%
  5. Paxil: 6 people, 20.00%
  6. Pepcid: 6 people, 20.00%
  7. Lortab: 6 people, 20.00%
  8. Lipitor: 6 people, 20.00%
  9. Prilosec: 6 people, 20.00%
  10. Fish Oil: 6 people, 20.00%

What are other side effects people have besides Hot flush? *

  1. Headache (pain in head): 20 people, 66.67%
  2. Fatigue (feeling of tiredness): 16 people, 53.33%
  3. Pain: 14 people, 46.67%
  4. Stress And Anxiety: 12 people, 40.00%
  5. Weakness: 12 people, 40.00%
  6. Diarrhea: 11 people, 36.67%
  7. Weight Decreased: 10 people, 33.33%
  8. Joint Pain: 10 people, 33.33%
  9. High Blood Pressure: 10 people, 33.33%
  10. Sinus Congestion (blockage of sinus): 10 people, 33.33%

What are the existing conditions these people have? *

  1. Metastases To Bone (cancer spreads to bone): 6 people, 20.00%
  2. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 5 people, 16.67%
  3. Sciatica (a set of symptoms including pain caused by general compression or irritation of one of five spinal nerve roots of each sciatic nerve): 3 people, 10.00%
  4. Intervertebral Disc Protrusion (spinal disc protrusion): 3 people, 10.00%
  5. Osteopenia (a condition where bone mineral density is lower than normal): 3 people, 10.00%
  6. Allergic Rhinitis: 2 people, 6.67%
  7. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 6.67%
  8. Stress And Anxiety: 2 people, 6.67%
  9. Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder): 2 people, 6.67%
  10. Neuralgia (pain in one or more nerves): 2 people, 6.67%

* Approximation only. Some reports may have incomplete information.

Do you take Depo-medrol and have Hot flush?

- Check whether Hot flush is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Depo-medrol:

Hot flush treatments and more:

How severe was Hot flush and when was it recovered:

Expand to all the drugs that have ingredients of methylprednisolone acetate:

Sub-studies by age:

0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Depo-medrol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hot flush:

Browse all the conditions that are associated with Hot flush:


How the study uses the data?

The study uses data from the FDA. It is based on methylprednisolone acetate (the active ingredients of Depo-medrol) and Depo-medrol (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe: