Depo-medrol and Osteopenia - a phase IV clinical study of FDA data

Summary:

Osteopenia is reported as a side effect among people who take Depo-medrol (methylprednisolone acetate), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Premarin, and have Rheumatoid arthritis.

The phase IV clinical study analyzes which people have Osteopenia when taking Depo-medrol. It is created by eHealthMe based on reports of 5,847 people who have side effects when taking Depo-medrol from the FDA, and is updated regularly.

What is Depo-medrol?

Depo-medrol has active ingredients of methylprednisolone acetate. It is often used in birth control. eHealthMe is studying from 5,933 Depo-medrol users. Check the latest studies of Depo-medrol.

What is Osteopenia?

Osteopenia (a condition where bone mineral density is lower than normal) is found to be associated with 1,446 drugs and 1,170 conditions by eHealthMe. Check the latest studies of Osteopenia.

On Jul, 12, 2026

5,847 people reported to have side effects when taking Depo-medrol.
Among them, 122 people (2.09%) have Osteopenia.

Among these 122 people:

* Approximation only. Some reports may have incomplete information.

Do you take Depo-medrol and have Osteopenia?

- Check whether Osteopenia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Depo-medrol:

Depo-medrol (5,933 reports)

Osteopenia treatments and more:

Osteopenia (46,948 reports)

How severe was Osteopenia and when was it recovered:

Osteopenia in Depo-medrol

Expand to all the drugs that have ingredients of methylprednisolone acetate:

Osteopenia and drugs with ingredients of methylprednisolone acetate (71 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Depo-medrol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Osteopenia:

Osteopenia (1,446 drugs)

Browse all the conditions that are associated with Osteopenia:

Osteopenia (1,170 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on methylprednisolone acetate (the active ingredients of Depo-medrol) and Depo-medrol (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.