Depodur and Constipation - a phase IV clinical study of FDA data

Summary:

Constipation is reported as a side effect among people who take Depodur (morphine sulfate), especially for people who are male, 60+ old, also take Percocet,.

The phase IV clinical study analyzes which people have Constipation when taking Depodur. It is created by eHealthMe based on reports of 1,624 people who have side effects when taking Depodur from the FDA, and is updated regularly.

What is Depodur?

Depodur has active ingredients of morphine sulfate. eHealthMe is studying from 1,625 Depodur users. Check the latest studies of Depodur.

What is Constipation?

Constipation is found to be associated with 3,004 drugs and 4,609 conditions by eHealthMe. Check the latest studies of Constipation.



On Jul, 08, 2026

1,624 people reported to have side effects when taking Depodur.
Among them, 26 people (1.6%) have Constipation.

Could Depodur cause Constipation?

Among these 26 people:

What is the gender of people who have Constipation when taking Depodur? *

  • female: 33.33 %
  • male: 66.67 %

What is the age of people who have Constipation when taking Depodur? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 0.0 %
  • 60+: 100 %

What are other drugs people take besides Depodur? *

  1. Percocet: 23 people, 88.46%
  2. Morphine Sulfate: 21 people, 80.77%
  3. Fentanyl Citrate: 18 people, 69.23%
  4. Tramadol Hydrochloride: 17 people, 65.38%
  5. Opana Er: 14 people, 53.85%
  6. Opana: 13 people, 50.00%
  7. Belbuca: 12 people, 46.15%
  8. Oxymorphone Hydrochloride: 10 people, 38.46%
  9. Buprenorphine Hydrochloride: 9 people, 34.62%
  10. Hydrocodone Polistirex And Chlorpheniramine Polistirex: 8 people, 30.77%

What are other side effects people have besides Constipation? *

  1. Overdose: 9 people, 34.62%
  2. Nausea (feeling of having an urge to vomit): 7 people, 26.92%
  3. Dizziness: 5 people, 19.23%
  4. Depression: 5 people, 19.23%
  5. Stress And Anxiety: 5 people, 19.23%
  6. Drowsiness: 4 people, 15.38%
  7. Memory Loss: 4 people, 15.38%
  8. Respiratory Depression (respiration has a rate below 12 breaths): 4 people, 15.38%
  9. Confusional State: 3 people, 11.54%
  10. Nightmares (unpleasant dreams): 3 people, 11.54%

* Approximation only. Some reports may have incomplete information.

Do you take Depodur and have Constipation?

- Check whether Constipation is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Depodur:

Constipation treatments and more:

How severe was Constipation and when was it recovered:

Expand to all the drugs that have ingredients of morphine sulfate:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Depodur:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Constipation:

Browse all the conditions that are associated with Constipation:

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on morphine sulfate (the active ingredients of Depodur) and Depodur (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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