Depodur and Sedation aggravated - a phase IV clinical study of FDA data

Summary:

Sedation aggravated is reported as a side effect among people who take Depodur (morphine sulfate), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Fentanyl, and have Pain.

The phase IV clinical study analyzes which people have Sedation aggravated when taking Depodur. It is created by eHealthMe based on reports of 1,624 people who have side effects when taking Depodur from the FDA, and is updated regularly.

What is Depodur?

Depodur has active ingredients of morphine sulfate. eHealthMe is studying from 1,625 Depodur users. Check the latest studies of Depodur.

What is Sedation aggravated?

Sedation aggravated is found to be associated with 1,159 drugs and 497 conditions by eHealthMe. Check the latest studies of Sedation aggravated.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 31, 2026

1,624 people reported to have side effects when taking Depodur.
Among them, 23 people (1.42%) have Sedation aggravated.

Could Depodur cause Sedation aggravated?

Among these 23 people:

How long have people been on Depodur when they have Sedation aggravated? *

What is the gender of people who have Sedation aggravated when taking Depodur? *

female: 73.91 %
male: 26.09 %

What is the age of people who have Sedation aggravated when taking Depodur? *

What are other drugs people take besides Depodur? *

What are other side effects people have besides Sedation aggravated? *

Oxygen Saturation Decreased: 11 people, 47.83%
Respiratory Depression (respiration has a rate below 12 breaths): 9 people, 39.13%
Nausea (feeling of having an urge to vomit): 4 people, 17.39%
Drowsiness: 4 people, 17.39%
Respiratory Rate Decreased (less breathing rate/min): 4 people, 17.39%
Intestinal Obstruction: 4 people, 17.39%
Itching: 4 people, 17.39%
Dizziness: 3 people, 13.04%
Apnea (temporary absence or cessation of breathing): 3 people, 13.04%
Depressed Level Of Consciousness: 3 people, 13.04%

What are the existing conditions these people have? *

Pain: 4 people, 17.39%
Procedural Pain: 3 people, 13.04%
Post Procedural Pain: 1 person, 4.35%
Post Procedural Complication: 1 person, 4.35%
Nausea (feeling of having an urge to vomit): 1 person, 4.35%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 1 person, 4.35%

* Approximation only. Some reports may have incomplete information.

Do you take Depodur and have Sedation aggravated?

- Check whether Sedation aggravated is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Depodur:

Depodur (1,625 reports)

Browse all side effects of Depodur:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Sedation aggravated:

Sedation aggravated (1,160 drugs)

Browse all the conditions that are associated with Sedation aggravated:

Sedation aggravated (497 conditions)

Related publications that referenced our studies

Rasmy A, Rahal M, Kisana M, Ahmad S, Salah A, "Morphine induced thrombocytopenia: A case report", Journal of Case Reports and Images in Oncology, 2015 Dec .
Rasmy A, Rahal M, Kisana M, Ahmad S, Salah A, "Morphine induced thrombocytopenia: A case report", Journal of Case Reports and Images in Oncology, 2015 Dec .

How the study uses the data?

The study uses data from the FDA. It is based on morphine sulfate (the active ingredients of Depodur) and Depodur (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.