Descovy and Peripheral swelling - a phase IV clinical study of FDA data

Summary:

Peripheral swelling is reported as a side effect among people who take Descovy (emtricitabine; tenofovir alafenamide fumarate), especially for people who are male, 60+ old, have been taking the drug for 2 - 5 years also take Tivicay, and have Multiple myeloma.

The phase IV clinical study analyzes which people have Peripheral swelling when taking Descovy. It is created by eHealthMe based on reports of 14,206 people who have side effects when taking Descovy from the FDA, and is updated regularly.

What is Descovy?

Descovy has active ingredients of emtricitabine; tenofovir alafenamide fumarate. It is often used in hiv infection. eHealthMe is studying from 14,260 Descovy users. Check the latest studies of Descovy.

What is Peripheral swelling?

Peripheral swelling is found to be associated with 2,180 drugs and 1,741 conditions by eHealthMe. Check the latest studies of Peripheral swelling.

On Jul, 12, 2026

14,206 people reported to have side effects when taking Descovy.
Among them, 28 people (0.2%) have Peripheral swelling.

Could Descovy cause Peripheral swelling?

Among these 28 people:

How long have people been on Descovy when they have Peripheral swelling? *

What is the gender of people who have Peripheral swelling when taking Descovy? *

female: 36 %
male: 64 %

What is the age of people who have Peripheral swelling when taking Descovy? *

What are other drugs people take besides Descovy? *

What are other side effects people have besides Peripheral swelling? *

Pain: 8 people, 28.57%
Fatigue (feeling of tiredness): 8 people, 28.57%
Chronic Kidney Disease: 5 people, 17.86%
Pain In Extremity: 5 people, 17.86%
Emotional Distress: 5 people, 17.86%
Rashes (redness): 5 people, 17.86%
Insomnia (sleeplessness): 4 people, 14.29%
Renal Disorder (kidney disease): 4 people, 14.29%
Acute Kidney Failure: 4 people, 14.29%
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect): 4 people, 14.29%

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 3 people, 10.71%
Psoriasis (immune-mediated disease that affects the skin): 2 people, 7.14%
Neuropathy Peripheral (surface nerve damage): 2 people, 7.14%
Weight Decreased: 1 person, 3.57%
Thyroid Cancer: 1 person, 3.57%
Pulmonary Hypertension (increase in blood pressure in the lung artery): 1 person, 3.57%
Lipodystrophy Acquired (a regional loss of subcutaneous adipose tissue which usually starts in the face, extends downward acquired): 1 person, 3.57%
High Blood Pressure: 1 person, 3.57%
High Blood Cholesterol: 1 person, 3.57%
Diabetes: 1 person, 3.57%

* Approximation only. Some reports may have incomplete information.

Do you take Descovy and have Peripheral swelling?

- Check whether Peripheral swelling is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Descovy:

Descovy (14,260 reports)

Peripheral swelling treatments and more:

Peripheral swelling (168,738 reports)

How severe was Peripheral swelling and when was it recovered:

Peripheral swelling in Descovy

Expand to all the drugs that have ingredients of emtricitabine; tenofovir alafenamide fumarate:

Peripheral swelling and drugs with ingredients of emtricitabine; tenofovir alafenamide fumarate

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Descovy:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Peripheral swelling:

Peripheral swelling (2,180 drugs)

Browse all the conditions that are associated with Peripheral swelling:

Peripheral swelling (1,741 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on emtricitabine; tenofovir alafenamide fumarate (the active ingredients of Descovy) and Descovy (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.