Descovy and Tendon rupture - a phase IV clinical study of FDA data

Summary:

Tendon rupture is reported as a side effect among people who take Descovy (emtricitabine; tenofovir alafenamide fumarate), especially for people who are male, 50-59 old, also take Truvada, and have Bone pain.

The phase IV clinical study analyzes which people have Tendon rupture when taking Descovy. It is created by eHealthMe based on reports of 14,206 people who have side effects when taking Descovy from the FDA, and is updated regularly.

What is Descovy?

Descovy has active ingredients of emtricitabine; tenofovir alafenamide fumarate. It is often used in hiv infection. eHealthMe is studying from 14,260 Descovy users. Check the latest studies of Descovy.

What is Tendon rupture?

Tendon rupture (tear of tendon) is found to be associated with 803 drugs and 1,060 conditions by eHealthMe. Check the latest studies of Tendon rupture.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

14,206 people reported to have side effects when taking Descovy.
Among them, 16 people (0.11%) have Tendon rupture.

Among these 16 people:

What is the gender of people who have Tendon rupture when taking Descovy? *

female: 0.0 %
male: 100 %

What is the age of people who have Tendon rupture when taking Descovy? *

What are other drugs people take besides Descovy? *

What are other side effects people have besides Tendon rupture? *

Bone Density Decreased: 7 people, 43.75%
Emotional Distress: 6 people, 37.50%
Arthropathy: 6 people, 37.50%
Bone Loss: 6 people, 37.50%
Pain: 6 people, 37.50%
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 6 people, 37.50%
Renal Impairment (severely reduced kidney function): 5 people, 31.25%
Multiple Fractures: 5 people, 31.25%
Osteoporosis (bones weak and more likely to break): 5 people, 31.25%
Osteopenia (a condition where bone mineral density is lower than normal): 5 people, 31.25%

What are the existing conditions these people have? *

Viral Infection: 2 people, 12.50%
Stress And Anxiety: 2 people, 12.50%
Quit Smoking: 2 people, 12.50%
Pain: 2 people, 12.50%
Nausea (feeling of having an urge to vomit): 2 people, 12.50%
Hyperlipidaemia (presence of excess lipids in the blood): 2 people, 12.50%
High Blood Cholesterol: 2 people, 12.50%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 12.50%
Depression: 2 people, 12.50%
Bone Pain: 2 people, 12.50%

* Approximation only. Some reports may have incomplete information.

Do you take Descovy and have Tendon rupture?

- Check whether Tendon rupture is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Descovy:

Descovy (14,260 reports)

Tendon rupture treatments and more:

Tendon rupture (15,907 reports)

How severe was Tendon rupture and when was it recovered:

Tendon rupture in Descovy

Expand to all the drugs that have ingredients of emtricitabine; tenofovir alafenamide fumarate:

Tendon rupture and drugs with ingredients of emtricitabine; tenofovir alafenamide fumarate

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Descovy:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Tendon rupture:

Tendon rupture (803 drugs)

Browse all the conditions that are associated with Tendon rupture:

Tendon rupture (1,060 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on emtricitabine; tenofovir alafenamide fumarate (the active ingredients of Descovy) and Descovy (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.