Desferal and Oedema - a phase IV clinical study of FDA data

Summary:

Oedema is reported as a side effect among people who take Desferal (deferoxamine mesylate), especially for people who are male, 60+ old, have been taking the drug for 6 - 12 months also take Exjade, and have Myelodysplastic syndrome.

The phase IV clinical study analyzes which people have Oedema when taking Desferal. It is created by eHealthMe based on reports of 2,241 people who have side effects when taking Desferal from the FDA, and is updated regularly.

What is Desferal?

Desferal has active ingredients of deferoxamine mesylate. It is often used in iron overload. eHealthMe is studying from 2,248 Desferal users. Check the latest studies of Desferal.

What is Oedema?

Oedema (fluid collection in tissue) is found to be associated with 2,194 drugs and 2,311 conditions by eHealthMe. Check the latest studies of Oedema.



On Jul, 20, 2026

2,241 people reported to have side effects when taking Desferal.
Among them, 29 people (1.29%) have Oedema.

Could Desferal cause Oedema?

Among these 29 people:

How long have people been on Desferal when they have Oedema? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 100 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Oedema when taking Desferal? *

  • female: 41.38 %
  • male: 58.62 %

What is the age of people who have Oedema when taking Desferal? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 20 %
  • 20-29: 8 %
  • 30-39: 4 %
  • 40-49: 12 %
  • 50-59: 28 %
  • 60+: 28 %

What are other drugs people take besides Desferal? *

  1. Exjade: 14 people, 48.28%
  2. Gliclazide: 4 people, 13.79%
  3. Ferriprox: 4 people, 13.79%
  4. Cyclosporine: 2 people, 6.90%
  5. Lunesta: 2 people, 6.90%
  6. Methotrexate: 2 people, 6.90%
  7. Duragesic-100: 2 people, 6.90%
  8. Zoloft: 2 people, 6.90%
  9. Oseltamivir Phosphate: 2 people, 6.90%
  10. Danocrine: 1 person, 3.45%

What are other side effects people have besides Oedema? *

  1. Nausea (feeling of having an urge to vomit): 7 people, 24.14%
  2. Dyspnea (difficult or laboured breathing): 6 people, 20.69%
  3. Weight Decreased: 6 people, 20.69%
  4. Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 6 people, 20.69%
  5. Pulmonary Hypertension (increase in blood pressure in the lung artery): 5 people, 17.24%
  6. Cardiac Failure: 5 people, 17.24%
  7. Acute Kidney Failure: 5 people, 17.24%
  8. Malaise (a feeling of general discomfort or uneasiness): 5 people, 17.24%
  9. Anorexia (eating disorder characterized by immoderate food restriction and irrational fear of gaining weight): 5 people, 17.24%
  10. Skin Discoloration - Bluish (bluish colour of skin): 5 people, 17.24%

What are the existing conditions these people have? *

  1. Myelodysplastic Syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged): 4 people, 13.79%
  2. Serum Ferritin Increased: 2 people, 6.90%
  3. Pain: 2 people, 6.90%
  4. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 2 people, 6.90%
  5. Haemosiderosis (general increase in tissue iron stores without associated tissue damage): 2 people, 6.90%
  6. Dry Skin: 2 people, 6.90%
  7. Depression: 2 people, 6.90%
  8. Aplastic Anemia: 2 people, 6.90%
  9. Osteoporosis (bones weak and more likely to break): 1 person, 3.45%
  10. Osteopenia (a condition where bone mineral density is lower than normal): 1 person, 3.45%

* Approximation only. Some reports may have incomplete information.

Do you take Desferal and have Oedema?

- Check whether Oedema is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Desferal:

Oedema treatments and more:

How severe was Oedema and when was it recovered:

Expand to all the drugs that have ingredients of deferoxamine mesylate:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Desferal:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Oedema:

Browse all the conditions that are associated with Oedema:


How the study uses the data?

The study uses data from the FDA. It is based on deferoxamine mesylate (the active ingredients of Desferal) and Desferal (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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