Desogen and Pain - a phase IV clinical study of FDA data

Summary:

Pain is reported as a side effect among people who take Desogen (desogestrel; ethinyl estradiol), especially for people who are female, 30-39 old, have been taking the drug for 2 - 5 years also take Yasmin, and have Nausea.

The phase IV clinical study analyzes which people have Pain when taking Desogen. It is created by eHealthMe based on reports of 553 people who have side effects when taking Desogen from the FDA, and is updated regularly.

What is Desogen?

Desogen has active ingredients of desogestrel; ethinyl estradiol. It is often used in birth control. eHealthMe is studying from 664 Desogen users. Check the latest studies of Desogen.

What is Pain?

Pain is found to be associated with 3,806 drugs and 5,872 conditions by eHealthMe. Check the latest studies of Pain.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Sep, 02, 2026

553 people reported to have side effects when taking Desogen.
Among them, 31 people (5.61%) have Pain.

Could Desogen cause Pain?

Among these 31 people:

How long have people been on Desogen when they have Pain? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 25 %
  • 2 - 5 years: 75 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Pain when taking Desogen? *

  • female: 96.77 %
  • male: 3.23 %

What is the age of people who have Pain when taking Desogen? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 10.0 %
  • 20-29: 36.67 %
  • 30-39: 43.33 %
  • 40-49: 10.0 %
  • 50-59: 0.0 %
  • 60+: 0.0 %

What are other drugs people take besides Desogen? *

  1. Yasmin: 16 people, 51.61%
  2. Ibuprofen: 7 people, 22.58%
  3. Zofran: 6 people, 19.35%
  4. Drospirenone And Ethinyl Estradiol: 5 people, 16.13%
  5. Protonix: 5 people, 16.13%
  6. Yaz: 5 people, 16.13%
  7. Vicodin: 5 people, 16.13%
  8. Amoxicillin: 4 people, 12.90%
  9. Plavix: 4 people, 12.90%
  10. Excedrin: 4 people, 12.90%

What are other side effects people have besides Pain? *

  1. Gallstones (stone formation by bile component): 7 people, 22.58%
  2. Stress And Anxiety: 7 people, 22.58%
  3. Cognitive Disorder (mental health disorders affects learning, memory, perception, and problem solving): 6 people, 19.35%
  4. Injury: 5 people, 16.13%
  5. Cholecystitis Chronic (long lasting infection of gallbladder): 5 people, 16.13%
  6. Biliary Dyskinesia (motility disorder that affects the gallbladder and sphincter of oddi): 5 people, 16.13%
  7. Pulmonary Embolism (blockage of the main artery of the lung): 5 people, 16.13%
  8. Weight Decreased: 4 people, 12.90%
  9. Ischaemic Stroke (stroke; caused by an interruption in the flow of blood to the brain): 4 people, 12.90%
  10. Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 4 people, 12.90%

What are the existing conditions these people have? *

  1. Premenstrual Syndrome: 6 people, 19.35%
  2. Nausea (feeling of having an urge to vomit): 6 people, 19.35%
  3. Migraine (headache): 4 people, 12.90%
  4. Menstruation Irregular: 4 people, 12.90%
  5. Gastric Ulcer (stomach ulcer): 3 people, 9.68%
  6. Panic Disorder: 3 people, 9.68%
  7. Heavy Or Prolong Menstrual Bleeding: 3 people, 9.68%
  8. Stress And Anxiety: 2 people, 6.45%
  9. Acne (skin problems that cause pimples): 2 people, 6.45%
  10. Acute Lymphocytic Leukemia (All) (cancer of the white blood cells characterized by excess lymphoblasts): 1 person, 3.23%

* Approximation only. Some reports may have incomplete information.

Do you take Desogen and have Pain?

- Check whether Pain is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Desogen:

Pain treatments and more:

  • Pain (1,140,596 reports)

How severe was Pain and when was it recovered:

Expand to all the drugs that have ingredients of desogestrel; ethinyl estradiol:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Desogen:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Pain:

  • Pain (3,806 drugs)

Browse all the conditions that are associated with Pain:

  • Pain (5,872 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on desogestrel; ethinyl estradiol (the active ingredients of Desogen) and Desogen (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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