Detrol la and Aphonia - a phase IV clinical study of FDA data

Summary:

Aphonia is reported as a side effect among people who take Detrol la (tolterodine tartrate), especially for people who are female, 60+ old, have been taking the drug for 1 - 2 years also take Synthroid, and have Hypertonic bladder.

The phase IV clinical study analyzes which people have Aphonia when taking Detrol la. It is created by eHealthMe based on reports of 13,073 people who have side effects when taking Detrol la from the FDA, and is updated regularly.

What is Detrol la?

Detrol la has active ingredients of tolterodine tartrate. It is often used in urge incontinence. eHealthMe is studying from 13,358 Detrol la users. Check the latest studies of Detrol la.

What is Aphonia?

Aphonia (inability to produce voice) is found to be associated with 887 drugs and 840 conditions by eHealthMe. Check the latest studies of Aphonia.

On Jul, 14, 2026

13,073 people reported to have side effects when taking Detrol la.
Among them, 16 people (0.12%) have Aphonia.

Among these 16 people:

How long have people been on Detrol la when they have Aphonia? *

What is the gender of people who have Aphonia when taking Detrol la? *

female: 93.75 %
male: 6.25 %

What is the age of people who have Aphonia when taking Detrol la? *

What are other drugs people take besides Detrol la? *

What are other side effects people have besides Aphonia? *

Vocal Cord Disorder: 5 people, 31.25%
Hernia (hernia happens when part of an internal organ or tissue bulges through a weak area of muscle): 4 people, 25.00%
Dry Mouth: 4 people, 25.00%
Malaise (a feeling of general discomfort or uneasiness): 3 people, 18.75%
Feeling Abnormal: 3 people, 18.75%
Nasopharyngitis (inflammation of the nasopharynx): 3 people, 18.75%
Headache (pain in head): 2 people, 12.50%
Dyspnea (difficult or laboured breathing): 1 person, 6.25%
Drug Hypersensitivity: 1 person, 6.25%
Drowsiness: 1 person, 6.25%

What are the existing conditions these people have? *

Hypertonic Bladder (bladder-storage function that causes a sudden urge to urinate): 7 people, 43.75%
Pollakiuria (abnormally frequent passage of relatively small quantities or urine): 4 people, 25.00%
High Blood Pressure: 3 people, 18.75%
Thyroid Diseases: 3 people, 18.75%
Pain In Extremity: 1 person, 6.25%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 1 person, 6.25%
Indigestion: 1 person, 6.25%
Increased Upper Airway Secretion: 1 person, 6.25%
Ill-Defined Disorder: 1 person, 6.25%
Stress And Anxiety: 1 person, 6.25%

* Approximation only. Some reports may have incomplete information.

Do you take Detrol la and have Aphonia?

- Check whether Aphonia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Detrol la:

Detrol la (13,358 reports)

Aphonia treatments and more:

Aphonia (15,979 reports)

Browse all side effects of Detrol la:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Aphonia:

Aphonia (887 drugs)

Browse all the conditions that are associated with Aphonia:

Aphonia (840 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on tolterodine tartrate (the active ingredients of Detrol la) and Detrol la (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.