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Dexrazoxane and Fatigue - a phase IV clinical study of FDA data

Summary:

Fatigue is reported as a side effect among people who take Dexrazoxane (dexrazoxane hydrochloride), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Neulasta, and have Breast cancer.

The phase IV clinical study analyzes which people have Fatigue when taking Dexrazoxane. It is created by eHealthMe based on reports of 1,140 people who have side effects when taking Dexrazoxane from the FDA, and is updated regularly.

What is Dexrazoxane?

Dexrazoxane has active ingredients of dexrazoxane hydrochloride. eHealthMe is studying from 1,141 Dexrazoxane users. Check the latest studies of Dexrazoxane.

What is Fatigue?

Fatigue (feeling of tiredness) is found to be associated with 4,027 drugs and 6,382 conditions by eHealthMe. Check the latest studies of Fatigue.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Aug, 05, 2026

1,140 people reported to have side effects when taking Dexrazoxane.
Among them, 16 people (1.4%) have Fatigue.

Could Dexrazoxane cause Fatigue?

Among these 16 people:

How long have people been on Dexrazoxane when they have Fatigue? *

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Fatigue when taking Dexrazoxane? *

  • female: 69.23 %
  • male: 30.77 %

What is the age of people who have Fatigue when taking Dexrazoxane? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 15.38 %
  • 20-29: 0.0 %
  • 30-39: 7.69 %
  • 40-49: 23.08 %
  • 50-59: 23.08 %
  • 60+: 30.77 %

What are other drugs people take besides Dexrazoxane? *

  1. Neulasta: 3 people, 18.75%
  2. Adriamycin Pfs: 2 people, 12.50%
  3. Senna: 2 people, 12.50%
  4. Morphine: 2 people, 12.50%
  5. Dexamethasone: 2 people, 12.50%
  6. Ondansetron: 2 people, 12.50%
  7. Oxycodone: 2 people, 12.50%
  8. Lansoprazole: 2 people, 12.50%
  9. Afinitor: 2 people, 12.50%
  10. Amlodipine: 1 person, 6.25%

What are other side effects people have besides Fatigue? *

  1. Nausea (feeling of having an urge to vomit): 8 people, 50.00%
  2. Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 7 people, 43.75%
  3. Diarrhea: 7 people, 43.75%
  4. Febrile Neutropenia (fever with reduced white blood cells): 6 people, 37.50%
  5. Anaemia (lack of blood): 5 people, 31.25%
  6. Fever: 5 people, 31.25%
  7. Thrombocytopenia (decrease of platelets in blood): 5 people, 31.25%
  8. Nausea And Vomiting: 5 people, 31.25%
  9. Constipation: 4 people, 25.00%
  10. White Blood Cell Count Decreased: 3 people, 18.75%

What are the existing conditions these people have? *

  1. Sarcoma (rare cancers that develop in the muscle, bone, nerves, cartilage, tendons, blood vessels and the fatty and fibrous tissues): 2 people, 12.50%
  2. Rhabdomyosarcoma (cancer of the bone, soft tissues, or connective tissue (e.g., tendon or cartilage)): 2 people, 12.50%
  3. Acute Lymphocytic Leukemia (All) (cancer of the white blood cells characterized by excess lymphoblasts): 2 people, 12.50%
  4. Nausea And Vomiting: 2 people, 12.50%
  5. Breast Cancer: 2 people, 12.50%
  6. Sleep Disorder: 1 person, 6.25%
  7. Depression: 1 person, 6.25%
  8. Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 1 person, 6.25%
  9. Breast Cancer Metastatic: 1 person, 6.25%
  10. Burkitt Lymphoma (cancer of the lymphatic system): 1 person, 6.25%

* Approximation only. Some reports may have incomplete information.

Do you take Dexrazoxane and have Fatigue?

- Check whether Fatigue is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Dexrazoxane:

Fatigue treatments and more:

How severe was Fatigue and when was it recovered:

Expand to all the drugs that have ingredients of dexrazoxane hydrochloride:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Dexrazoxane:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Fatigue:

Browse all the conditions that are associated with Fatigue:

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on dexrazoxane hydrochloride (the active ingredients of Dexrazoxane) and Dexrazoxane (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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