Differin and Dysphasia - a phase IV clinical study of FDA data

Summary:

Dysphasia is reported as a side effect among people who take Differin (adapalene), especially for people who are female, 10-19 old, also take Nasacort, and have Depression.

The phase IV clinical study analyzes which people have Dysphasia when taking Differin. It is created by eHealthMe based on reports of 5,708 people who have side effects when taking Differin from the FDA, and is updated regularly.

What is Differin?

Differin has active ingredients of adapalene. It is often used in acne. eHealthMe is studying from 5,740 Differin users. Check the latest studies of Differin.

What is Dysphasia?

Dysphasia (language disorder marked by deficiency in the generation of speech) is found to be associated with 3,376 drugs and 3,573 conditions by eHealthMe. Check the latest studies of Dysphasia.

On Jun, 21, 2026

5,708 people reported to have side effects when taking Differin.
Among them, 11 people (0.19%) have Dysphasia.

Among these 11 people:

What is the gender of people who have Dysphasia when taking Differin? *

female: 81.82 %
male: 18.18 %

What is the age of people who have Dysphasia when taking Differin? *

What are other drugs people take besides Differin? *

What are other side effects people have besides Dysphasia? *

Fatigue (feeling of tiredness): 7 people, 63.64%
White Blood Cell Count Increased: 6 people, 54.55%
Personality Change: 6 people, 54.55%
Activated Partial Thromboplastin Time Shortened: 6 people, 54.55%
Back Pain: 6 people, 54.55%
Cheilitis (infection of lips): 6 people, 54.55%
Feeling Abnormal: 6 people, 54.55%
High Blood Cholesterol: 6 people, 54.55%
Hypertriglyceridaemia (excess of triglycerides in the blood): 6 people, 54.55%
Weight Decreased: 6 people, 54.55%

What are the existing conditions these people have? *

Depression: 3 people, 27.27%
Birth Control: 2 people, 18.18%
Premenstrual Syndrome: 1 person, 9.09%
Polycystic Ovary Disease (cysts in the ovaries that occurs when the follicle stops developing): 1 person, 9.09%
Parkinson's Disease: 1 person, 9.09%
Pain: 1 person, 9.09%
Migraine (headache): 1 person, 9.09%
Infection: 1 person, 9.09%
Heavy Or Prolong Menstrual Bleeding: 1 person, 9.09%
Dysmenorrhea (painful menstruation): 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Differin and have Dysphasia?

- Check whether Dysphasia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Differin:

Differin (5,740 reports)

Dysphasia treatments and more:

Dysphasia (82,511 reports)

Browse all side effects of Differin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Dysphasia:

Dysphasia (3,376 drugs)

Browse all the conditions that are associated with Dysphasia:

Dysphasia (3,573 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on adapalene (the active ingredients of Differin) and Differin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.