Differin and Panic attack - a phase IV clinical study of FDA data

Summary:

Panic attack is reported as a side effect among people who take Differin (adapalene), especially for people who are female, 20-29 old, have been taking the drug for 6 - 12 months also take Paxil, and have Osteoporosis.

The phase IV clinical study analyzes which people have Panic attack when taking Differin. It is created by eHealthMe based on reports of 5,708 people who have side effects when taking Differin from the FDA, and is updated regularly.

What is Differin?

Differin has active ingredients of adapalene. It is often used in acne. eHealthMe is studying from 5,740 Differin users. Check the latest studies of Differin.

What is Panic attack?

Panic attack is found to be associated with 2,202 drugs and 2,082 conditions by eHealthMe. Check the latest studies of Panic attack.



On Jun, 27, 2026

5,708 people reported to have side effects when taking Differin.
Among them, 18 people (0.32%) have Panic attack.

Could Differin cause Panic attack?

Among these 18 people:

How long have people been on Differin when they have Panic attack? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 25 %
  • 6 - 12 months: 75 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Panic attack when taking Differin? *

  • female: 94.12 %
  • male: 5.88 %

What is the age of people who have Panic attack when taking Differin? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 35.71 %
  • 20-29: 35.71 %
  • 30-39: 7.14 %
  • 40-49: 7.14 %
  • 50-59: 14.29 %
  • 60+: 0.0 %

What are other drugs people take besides Differin? *

  1. Paxil: 8 people, 44.44%
  2. Accutane: 6 people, 33.33%
  3. Claritin: 6 people, 33.33%
  4. Nasacort: 5 people, 27.78%
  5. Ortho Tri-Cyclen: 5 people, 27.78%
  6. Zovirax: 3 people, 16.67%
  7. Retin-A: 3 people, 16.67%
  8. Nizoral: 3 people, 16.67%
  9. Benzaclin: 3 people, 16.67%
  10. Nitrofurantoin: 3 people, 16.67%

What are other side effects people have besides Panic attack? *

  1. Stress And Anxiety: 12 people, 66.67%
  2. Fatigue (feeling of tiredness): 9 people, 50.00%
  3. Feeling Abnormal: 8 people, 44.44%
  4. Back Pain: 8 people, 44.44%
  5. Swallowing Difficulty: 8 people, 44.44%
  6. Depression: 8 people, 44.44%
  7. Dyspnea (difficult or laboured breathing): 6 people, 33.33%
  8. High Blood Cholesterol: 6 people, 33.33%
  9. Agitation (state of anxiety or nervous excitement): 6 people, 33.33%
  10. Nasal Dryness (dry nose): 6 people, 33.33%

What are the existing conditions these people have? *

  1. Osteoporosis (bones weak and more likely to break): 4 people, 22.22%
  2. Osteopenia (a condition where bone mineral density is lower than normal): 3 people, 16.67%
  3. Hypersensitivity: 3 people, 16.67%
  4. Depression: 3 people, 16.67%
  5. Skin Wrinkling (wrinkle on skin): 1 person, 5.56%
  6. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 1 person, 5.56%
  7. Herpes Virus Infection: 1 person, 5.56%
  8. Growth Of Eyelashes: 1 person, 5.56%
  9. Drowsiness: 1 person, 5.56%
  10. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 1 person, 5.56%

* Approximation only. Some reports may have incomplete information.

Do you take Differin and have Panic attack?

- Check whether Panic attack is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Differin:

Panic attack treatments and more:

How severe was Panic attack and when was it recovered:

Expand to all the drugs that have ingredients of adapalene:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Differin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Panic attack:

Browse all the conditions that are associated with Panic attack:


How the study uses the data?

The study uses data from the FDA. It is based on adapalene (the active ingredients of Differin) and Differin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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