Diflunisal and Chills - a phase IV clinical study of FDA data

Summary:

Chills is reported as a side effect among people who take Diflunisal (diflunisal), especially for people who are male, 60+ old, have been taking the drug for 2 - 5 years also take Tegsedi, and have Hereditary neuropathic amyloidosis.

The phase IV clinical study analyzes which people have Chills when taking Diflunisal. It is created by eHealthMe based on reports of 927 people who have side effects when taking Diflunisal from the FDA, and is updated regularly.

What is Diflunisal?

Diflunisal has active ingredients of diflunisal. eHealthMe is studying from 945 Diflunisal users. Check the latest studies of Diflunisal.

What is Chills?

Chills (felling of cold) is found to be associated with 2,549 drugs and 3,475 conditions by eHealthMe. Check the latest studies of Chills.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 11, 2026

927 people reported to have side effects when taking Diflunisal.
Among them, 24 people (2.59%) have Chills.

Among these 24 people:

How long have people been on Diflunisal when they have Chills? *

What is the gender of people who have Chills when taking Diflunisal? *

female: 40 %
male: 60 %

What is the age of people who have Chills when taking Diflunisal? *

What are other drugs people take besides Diflunisal? *

What are other side effects people have besides Chills? *

Fatigue (feeling of tiredness): 14 people, 58.33%
Blood Creatine Phosphokinase Increased: 8 people, 33.33%
Nausea (feeling of having an urge to vomit): 8 people, 33.33%
Thrombocytopenia (decrease of platelets in blood): 7 people, 29.17%
Prealbumin Decreased: 7 people, 29.17%
Nausea And Vomiting: 7 people, 29.17%
Headache (pain in head): 7 people, 29.17%
Pain: 6 people, 25.00%
Diarrhea: 6 people, 25.00%
Fever: 6 people, 25.00%

What are the existing conditions these people have? *

Hereditary Neuropathic Amyloidosis (hereditary- diseases resulting from abnormal deposition of certain proteins (amyloid) in various bodily areas by problems with signals from the nerves): 17 people, 70.83%
Pain: 4 people, 16.67%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 12.50%
Vitamin A Deficiency: 2 people, 8.33%
Amyloidosis (a tumour within which amyloid is produced): 2 people, 8.33%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 2 people, 8.33%
Polyneuropathy (neurological disorder that occurs when many peripheral nerves throughout the body malfunction simultaneously): 2 people, 8.33%
Neuralgia (pain in one or more nerves): 2 people, 8.33%
Cardiac Amyloidosis (protein deposition in heart): 2 people, 8.33%
Blood Potassium Decreased: 1 person, 4.17%

* Approximation only. Some reports may have incomplete information.

Do you take Diflunisal and have Chills?

- Check whether Chills is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Diflunisal:

Diflunisal (945 reports)

Chills treatments and more:

Chills (145,628 reports)

Browse all side effects of Diflunisal:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Chills:

Chills (2,549 drugs)

Browse all the conditions that are associated with Chills:

Chills (3,475 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on diflunisal (the active ingredients of Diflunisal) and Diflunisal (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.