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Digoxin and Cachexia - a phase IV clinical study of FDA data

Summary:

Cachexia is reported as a side effect among people who take Digoxin (digoxin), especially for people who are female, 60+ old, have been taking the drug for 2 - 5 years also take Lasix, and have Cardiac failure congestive.

The phase IV clinical study analyzes which people have Cachexia when taking Digoxin. It is created by eHealthMe based on reports of 92,292 people who have side effects when taking Digoxin from the FDA, and is updated regularly.

What is Digoxin?

Digoxin has active ingredients of digoxin. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 93,738 Digoxin users. Check the latest studies of Digoxin.

What is Cachexia?

Cachexia (loss of weight) is found to be associated with 735 drugs and 1,194 conditions by eHealthMe. Check the latest studies of Cachexia.

On Oct, 22, 2025

92,292 people reported to have side effects when taking Digoxin.
Among them, 126 people (0.14%) have Cachexia.

Could Digoxin cause Cachexia?

Among these 126 people:

How long have people been on Digoxin when they have Cachexia? *

  • < 1 month: 9.09 %
  • 1 - 6 months: 9.09 %
  • 6 - 12 months: 18.18 %
  • 1 - 2 years: 21.21 %
  • 2 - 5 years: 24.24 %
  • 5 - 10 years: 9.09 %
  • 10+ years: 9.09 %

What is the gender of people who have Cachexia when taking Digoxin? *

  • female: 54.47 %
  • male: 45.53 %

What is the age of people who have Cachexia when taking Digoxin? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.97 %
  • 30-39: 2.91 %
  • 40-49: 1.94 %
  • 50-59: 4.85 %
  • 60+: 89.32 %

What are other drugs people take besides Digoxin? *

  1. Lasix: 44 people, 34.92%
  2. Coumadin: 40 people, 31.75%
  3. Aspirin: 33 people, 26.19%
  4. Coreg: 30 people, 23.81%
  5. Vicodin: 23 people, 18.25%
  6. Protonix: 23 people, 18.25%
  7. Nitroglycerin: 23 people, 18.25%
  8. Furosemide: 22 people, 17.46%
  9. Tylenol: 18 people, 14.29%
  10. Cardizem: 17 people, 13.49%

What are other side effects people have besides Cachexia? *

  1. Cardiac Failure Congestive: 53 people, 42.06%
  2. Dehydration (dryness resulting from the removal of water): 47 people, 37.30%
  3. Dyspnea (difficult or laboured breathing): 45 people, 35.71%
  4. Fatigue (feeling of tiredness): 44 people, 34.92%
  5. Acute Kidney Failure: 42 people, 33.33%
  6. Hypotension (abnormally low blood pressure): 41 people, 32.54%
  7. Pain: 41 people, 32.54%
  8. Weight Decreased: 41 people, 32.54%
  9. Weakness: 38 people, 30.16%
  10. Malnutrition (a condition that results from eating a diet in which certain nutrients are lacking): 38 people, 30.16%

What are the existing conditions these people have? *

  1. Cardiac Failure Congestive: 5 people, 3.97%
  2. Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 4 people, 3.17%
  3. Cardiac Disorder: 3 people, 2.38%
  4. Herpes Simplex (herpes simplex is a common viral infection): 3 people, 2.38%
  5. Cardiac Failure Chronic: 2 people, 1.59%
  6. Osteoporosis Post-Menopausal (weak bone with possibility to break after stopped menstrual cycles): 2 people, 1.59%
  7. Pain: 2 people, 1.59%
  8. Cardiac Failure: 2 people, 1.59%
  9. Pulmonary Hypertension (increase in blood pressure in the lung artery): 2 people, 1.59%
  10. Sleep Disorder: 2 people, 1.59%

* Approximation only. Some reports may have incomplete information.

Do you take Digoxin and have Cachexia?

- Check whether Cachexia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Digoxin:

Cachexia treatments and more:

How severe was Cachexia and when was it recovered:

Expand to all the drugs that have ingredients of digoxin:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Common Digoxin side effects:

Browse all side effects of Digoxin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Common drugs associated with Cachexia:

Browse all the drugs that are associated with Cachexia:

Common conditions associated with Cachexia:

Browse all the conditions that are associated with Cachexia:

Drugs similar to Digoxin and Cachexia :

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on digoxin (the active ingredients of Digoxin) and Digoxin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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