Digoxin and Haemolysis - a phase IV clinical study of FDA data
Summary:
Haemolysis is reported as a side effect among people who take Digoxin (digoxin), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Lasix, and have High blood pressure.
The phase IV clinical study analyzes which people have Haemolysis when taking Digoxin. It is created by eHealthMe based on reports of 92,292 people who have side effects when taking Digoxin from the FDA, and is updated regularly.
What is Digoxin?
Digoxin has active ingredients of digoxin. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 93,740 Digoxin users. Check the latest studies of Digoxin.
What is Haemolysis?
Haemolysis (breaking open of red blood cells and the release of haemoglobin into the surrounding fluid) is found to be associated with 612 drugs and 837 conditions by eHealthMe. Check the latest studies of Haemolysis.
92,292 people reported to have side effects when taking Digoxin.
Among them, 78 people (0.08%) have Haemolysis.

Among these 78 people:
How long have people been on Digoxin when they have Haemolysis? *
- < 1 month: 75 %
- 1 - 6 months: 0.0 %
- 6 - 12 months: 0.0 %
- 1 - 2 years: 0.0 %
- 2 - 5 years: 0.0 %
- 5 - 10 years: 25 %
- 10+ years: 0.0 %
What is the gender of people who have Haemolysis when taking Digoxin? *
- female: 44.59 %
- male: 55.41 %
What is the age of people who have Haemolysis when taking Digoxin? *
- 0-1: 2.82 %
- 2-9: 0.0 %
- 10-19: 0.0 %
- 20-29: 1.41 %
- 30-39: 5.63 %
- 40-49: 4.23 %
- 50-59: 25.35 %
- 60+: 60.56 %
What are other drugs people take besides Digoxin? *
- Lasix: 20 people, 25.64%
- Warfarin Sodium: 19 people, 24.36%
- Spironolactone: 13 people, 16.67%
- Soliris: 11 people, 14.10%
- Furosemide: 9 people, 11.54%
- Aldactone: 9 people, 11.54%
- Captopril: 9 people, 11.54%
- Norvasc: 9 people, 11.54%
- Lovenox: 8 people, 10.26%
- Aspirin: 8 people, 10.26%
What are other side effects people have besides Haemolysis? *
- Acute Kidney Failure: 15 people, 19.23%
- Anaemia (lack of blood): 15 people, 19.23%
- Hyperkalemia (damage to or disease of the kidney): 14 people, 17.95%
- Haemoglobin Decreased: 13 people, 16.67%
- Fatigue (feeling of tiredness): 10 people, 12.82%
- Hepatic Failure (liver failure): 10 people, 12.82%
- Thrombocytopenia (decrease of platelets in blood): 9 people, 11.54%
- Arrhythmias (irregular heartbeat): 8 people, 10.26%
- International Normalised Ratio Increased: 8 people, 10.26%
- Pneumonia: 7 people, 8.97%
What are the existing conditions these people have? *
- High Blood Pressure: 9 people, 11.54%
- Cardiac Failure: 7 people, 8.97%
- Paroxysmal Nocturnal Haemoglobinuria (haemoglobin in the urine): 6 people, 7.69%
- Pulmonary Hypertension Primary (increase in blood pressure in the lung artery with no cause): 4 people, 5.13%
- Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 3 people, 3.85%
- Irritable Bowel Syndrome: 3 people, 3.85%
- Blood Uric Acid Increased: 3 people, 3.85%
- Idiopathic Thrombocytopenic Purpura (bleeding disorder in which the immune system destroys platelets, which are necessary for normal blood clotting): 3 people, 3.85%
- Cardiac Disorder: 3 people, 3.85%
- Pain: 3 people, 3.85%
* Approximation only. Some reports may have incomplete information.
Do you take Digoxin and have Haemolysis?
- Check whether Haemolysis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, long term effects of, and alternative drugs to Digoxin:
- Digoxin (93,740 reports)
Haemolysis treatments and more:
- Haemolysis (9,155 reports)
How severe was Haemolysis and when was it recovered:
Expand to all the drugs that have ingredients of digoxin:
- Haemolysis and drugs with ingredients of digoxin (80 reports)
Sub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Digoxin:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all the drugs that are associated with Haemolysis:
- Haemolysis (612 drugs)
Browse all the conditions that are associated with Haemolysis:
- Haemolysis (837 conditions)
Related publications that referenced our studies
- Guru SR, Suresh A, Padmanabhan S, Reddy A, "A Rare Case of Digoxin Associated Gingival Overgrowth", Journal of clinical and diagnostic research: JCDR, 2017 Jan .
- Lai SW, Lin CL, Liao KF, "Digoxin use may increase the relative risk of acute pancreatitis: a population-based case–control study in Taiwan", International journal of cardiology, 2015 Feb .
- Guru SR, Suresh A, Padmanabhan S, Reddy A, "A Rare Case of Digoxin Associated Gingival Overgrowth", Journal of clinical and diagnostic research: JCDR, 2017 Jan .
- Lai SW, Lin CL, Liao KF, "Digoxin use may increase the relative risk of acute pancreatitis: a population-based case–control study in Taiwan", International journal of cardiology, 2015 Feb .
How the study uses the data?
The study uses data from the FDA. It is based on digoxin (the active ingredients of Digoxin) and Digoxin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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