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Digoxin and Hypercoagulation - a phase IV clinical study of FDA data

Summary:

Hypercoagulation is reported as a side effect among people who take Digoxin (digoxin), especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months also take Coumadin, and have Bone loss.

The phase IV clinical study analyzes which people have Hypercoagulation when taking Digoxin. It is created by eHealthMe based on reports of 92,292 people who have side effects when taking Digoxin from the FDA, and is updated regularly.

What is Digoxin?

Digoxin has active ingredients of digoxin. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 93,738 Digoxin users. Check the latest studies of Digoxin.

What is Hypercoagulation?

Hypercoagulation (increased tendency for clotting of the blood) is found to be associated with 446 drugs and 533 conditions by eHealthMe. Check the latest studies of Hypercoagulation.

On Oct, 06, 2025

92,292 people reported to have side effects when taking Digoxin.
Among them, 27 people (0.03%) have Hypercoagulation.

Could Digoxin cause Hypercoagulation?

Among these 27 people:

How long have people been on Digoxin when they have Hypercoagulation? *

  • < 1 month: 15.38 %
  • 1 - 6 months: 61.54 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 7.69 %
  • 2 - 5 years: 15.38 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Hypercoagulation when taking Digoxin? *

  • female: 74.07 %
  • male: 25.93 %

What is the age of people who have Hypercoagulation when taking Digoxin? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 17.39 %
  • 60+: 82.61 %

What are other drugs people take besides Digoxin? *

  1. Coumadin: 20 people, 74.07%
  2. Lasix: 14 people, 51.85%
  3. Aspirin: 12 people, 44.44%
  4. Coreg: 12 people, 44.44%
  5. Calan: 10 people, 37.04%
  6. Furosemide: 10 people, 37.04%
  7. Biaxin: 10 people, 37.04%
  8. Demadex: 9 people, 33.33%
  9. Coenzyme Q10: 9 people, 33.33%
  10. Centrum Silver: 9 people, 33.33%

What are other side effects people have besides Hypercoagulation? *

  1. Acute Kidney Failure: 16 people, 59.26%
  2. Weakness: 16 people, 59.26%
  3. Cardiac Failure Congestive: 15 people, 55.56%
  4. Nausea (feeling of having an urge to vomit): 15 people, 55.56%
  5. Diarrhea: 14 people, 51.85%
  6. Pleural Effusion (water on the lungs): 12 people, 44.44%
  7. Dehydration (dryness resulting from the removal of water): 12 people, 44.44%
  8. Nausea And Vomiting: 11 people, 40.74%
  9. Multiple Injuries: 11 people, 40.74%
  10. Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 11 people, 40.74%

What are the existing conditions these people have? *

  1. Osteoporosis (bones weak and more likely to break): 2 people, 7.41%
  2. Bone Loss: 2 people, 7.41%
  3. Stress And Anxiety: 1 person, 3.70%
  4. Restless Leg Syndrome (a powerful urge to move your legs): 1 person, 3.70%
  5. Lung Cancer - Non-Small Cell (lung cancer): 1 person, 3.70%
  6. Left Ventricular Dysfunction: 1 person, 3.70%
  7. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 1 person, 3.70%
  8. Diabetic Gastroparesis (paralysis of the muscles of the stomach caused by diabetes): 1 person, 3.70%
  9. Cardiac Disorder: 1 person, 3.70%
  10. Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 1 person, 3.70%

* Approximation only. Some reports may have incomplete information.

Do you take Digoxin and have Hypercoagulation?

- Check whether Hypercoagulation is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Digoxin:

Hypercoagulation treatments and more:

How severe was Hypercoagulation and when was it recovered:

Expand to all the drugs that have ingredients of digoxin:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Digoxin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hypercoagulation:

Browse all the conditions that are associated with Hypercoagulation:

Drugs similar to Digoxin and Hypercoagulation :

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on digoxin (the active ingredients of Digoxin) and Digoxin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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