Digoxin and Polymyalgia rheumatica aggravated - a phase IV clinical study of FDA data

Summary:

Polymyalgia rheumatica aggravated is reported as a side effect among people who take Digoxin (digoxin), especially for people who are male, 60+ old, have been taking the drug for 5 - 10 years also take Lisinopril, and have Toothaches.

The phase IV clinical study analyzes which people have Polymyalgia rheumatica aggravated when taking Digoxin. It is created by eHealthMe based on reports of 92,292 people who have side effects when taking Digoxin from the FDA, and is updated regularly.

What is Digoxin?

Digoxin has active ingredients of digoxin. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 93,740 Digoxin users. Check the latest studies of Digoxin.

What is Polymyalgia rheumatica aggravated?

Polymyalgia rheumatica aggravated (serious pain in many muscles) is found to be associated with 377 drugs and 336 conditions by eHealthMe. Check the latest studies of Polymyalgia rheumatica aggravated.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 04, 2026

92,292 people reported to have side effects when taking Digoxin.
Among them, 46 people (0.05%) have Polymyalgia rheumatica aggravated.

Could Digoxin cause Polymyalgia rheumatica aggravated?

Among these 46 people:

How long have people been on Digoxin when they have Polymyalgia rheumatica aggravated? *

What is the gender of people who have Polymyalgia rheumatica aggravated when taking Digoxin? *

female: 41.3 %
male: 58.7 %

What is the age of people who have Polymyalgia rheumatica aggravated when taking Digoxin? *

What are other drugs people take besides Digoxin? *

What are other side effects people have besides Polymyalgia rheumatica aggravated? *

Weakness: 26 people, 56.52%
Pain: 25 people, 54.35%
Pain In Extremity: 20 people, 43.48%
Cardiac Failure Congestive: 19 people, 41.30%
Dyspnea (difficult or laboured breathing): 18 people, 39.13%
Injury: 18 people, 39.13%
Fall: 17 people, 36.96%
Enlarged Heart: 17 people, 36.96%
Confusional State: 17 people, 36.96%
Back Pain: 16 people, 34.78%

What are the existing conditions these people have? *

Toothaches (tooth pain): 13 people, 28.26%
Muscle Spasms (muscle contraction): 11 people, 23.91%
Depression: 4 people, 8.70%
Sepsis (a severe blood infection that can lead to organ failure and death): 3 people, 6.52%
Bone Neoplasm Malignant (cancer of bone): 3 people, 6.52%
Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 3 people, 6.52%
High Blood Cholesterol: 2 people, 4.35%
Pain: 2 people, 4.35%
Stress And Anxiety: 2 people, 4.35%
Gout (uric acid crystals building up in the body): 1 person, 2.17%

* Approximation only. Some reports may have incomplete information.

Do you take Digoxin and have Polymyalgia rheumatica aggravated?

- Check whether Polymyalgia rheumatica aggravated is associated with a drug or a condition
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Digoxin:

Digoxin (93,740 reports)

Browse all side effects of Digoxin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Polymyalgia rheumatica aggravated:

Polymyalgia rheumatica aggravated (377 drugs)

Browse all the conditions that are associated with Polymyalgia rheumatica aggravated:

Polymyalgia rheumatica aggravated (336 conditions)

Related publications that referenced our studies

Guru SR, Suresh A, Padmanabhan S, Reddy A, "A Rare Case of Digoxin Associated Gingival Overgrowth", Journal of clinical and diagnostic research: JCDR, 2017 Jan .
Lai SW, Lin CL, Liao KF, "Digoxin use may increase the relative risk of acute pancreatitis: a population-based case–control study in Taiwan", International journal of cardiology, 2015 Feb .
Guru SR, Suresh A, Padmanabhan S, Reddy A, "A Rare Case of Digoxin Associated Gingival Overgrowth", Journal of clinical and diagnostic research: JCDR, 2017 Jan .
Lai SW, Lin CL, Liao KF, "Digoxin use may increase the relative risk of acute pancreatitis: a population-based case–control study in Taiwan", International journal of cardiology, 2015 Feb .

How the study uses the data?

The study uses data from the FDA. It is based on digoxin (the active ingredients of Digoxin) and Digoxin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.