Dilantin and Dry skin - a phase IV clinical study of FDA data

Summary:

Dry skin is reported as a side effect among people who take Dilantin (phenytoin sodium), especially for people who are male, 30-39 old, have been taking the drug for < 1 month also take Magnevist, and have Convulsion.

The phase IV clinical study analyzes which people have Dry skin when taking Dilantin. It is created by eHealthMe based on reports of 19,857 people who have side effects when taking Dilantin from the FDA, and is updated regularly.

What is Dilantin?

Dilantin has active ingredients of phenytoin sodium. It is often used in epilepsy. eHealthMe is studying from 20,858 Dilantin users. Check the latest studies of Dilantin.

What is Dry skin?

Dry skin is found to be associated with 1,998 drugs and 2,353 conditions by eHealthMe. Check the latest studies of Dry skin.



On Jul, 11, 2026

19,857 people reported to have side effects when taking Dilantin.
Among them, 88 people (0.44%) have Dry skin.

Could Dilantin cause Dry skin?

Among these 88 people:

How long have people been on Dilantin when they have Dry skin? *

  • < 1 month: 71.43 %
  • 1 - 6 months: 14.29 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 14.29 %
  • 10+ years: 0.0 %

What is the gender of people who have Dry skin when taking Dilantin? *

  • female: 43.68 %
  • male: 56.32 %

What is the age of people who have Dry skin when taking Dilantin? *

  • 0-1: 0.0 %
  • 2-9: 1.54 %
  • 10-19: 20.0 %
  • 20-29: 4.62 %
  • 30-39: 23.08 %
  • 40-49: 7.69 %
  • 50-59: 21.54 %
  • 60+: 21.54 %

What are other drugs people take besides Dilantin? *

  1. Magnevist: 21 people, 23.86%
  2. Renagel: 17 people, 19.32%
  3. Accutane: 17 people, 19.32%
  4. Optimark: 17 people, 19.32%
  5. Omniscan: 17 people, 19.32%
  6. Prednisone: 15 people, 17.05%
  7. Clonidine: 15 people, 17.05%
  8. Norvasc: 14 people, 15.91%
  9. Prohance: 13 people, 14.77%
  10. Multihance: 13 people, 14.77%

What are other side effects people have besides Dry skin? *

  1. Rashes (redness): 34 people, 38.64%
  2. Itching: 22 people, 25.00%
  3. Pain: 22 people, 25.00%
  4. Stress And Anxiety: 21 people, 23.86%
  5. Nephrogenic Systemic Fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease): 21 people, 23.86%
  6. Skin Hypertrophy (skin cells enlarges): 20 people, 22.73%
  7. Skin Induration (an abnormally hard spot or area on the skin): 18 people, 20.45%
  8. Oedema Peripheral (superficial swelling): 18 people, 20.45%
  9. Joint Range Of Motion Decreased (disease of joint movement): 17 people, 19.32%
  10. Skin Tightness: 17 people, 19.32%

What are the existing conditions these people have? *

  1. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 21 people, 23.86%
  2. Nuclear Magnetic Resonance Imaging Brain: 15 people, 17.05%
  3. Pain: 10 people, 11.36%
  4. High Blood Pressure: 9 people, 10.23%
  5. Neuralgia (pain in one or more nerves): 6 people, 6.82%
  6. High Blood Cholesterol: 5 people, 5.68%
  7. Acne (skin problems that cause pimples): 4 people, 4.55%
  8. Nuclear Magnetic Resonance Imaging Abdominal: 4 people, 4.55%
  9. Anaemia (lack of blood): 2 people, 2.27%
  10. Breast Cancer: 2 people, 2.27%

* Approximation only. Some reports may have incomplete information.

Do you take Dilantin and have Dry skin?

- Check whether Dry skin is associated with a drug or a condition
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Dilantin:

Dry skin treatments and more:

How severe was Dry skin and when was it recovered:

Expand to all the drugs that have ingredients of phenytoin sodium:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Dilantin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Dry skin:

Browse all the conditions that are associated with Dry skin:

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on phenytoin sodium (the active ingredients of Dilantin) and Dilantin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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