Dilantin and Hypomagnesaemia - a phase IV clinical study of FDA data

Summary:

Hypomagnesaemia is reported as a side effect among people who take Dilantin (phenytoin sodium), especially for people who are female, 50-59 old, also take Vicodin, and have Osteopenia.

The phase IV clinical study analyzes which people have Hypomagnesaemia when taking Dilantin. It is created by eHealthMe based on reports of 19,857 people who have side effects when taking Dilantin from the FDA, and is updated regularly.

What is Dilantin?

Dilantin has active ingredients of phenytoin sodium. It is often used in epilepsy. eHealthMe is studying from 20,858 Dilantin users. Check the latest studies of Dilantin.

What is Hypomagnesaemia?

Hypomagnesaemia (electrolyte disturbance in which there is an abnormally low level of magnesium in the blood) is found to be associated with 1,030 drugs and 1,053 conditions by eHealthMe. Check the latest studies of Hypomagnesaemia.

On Jul, 09, 2026

19,857 people reported to have side effects when taking Dilantin.
Among them, 15 people (0.08%) have Hypomagnesaemia.

Among these 15 people:

What is the gender of people who have Hypomagnesaemia when taking Dilantin? *

female: 60 %
male: 40 %

What is the age of people who have Hypomagnesaemia when taking Dilantin? *

What are other drugs people take besides Dilantin? *

What are other side effects people have besides Hypomagnesaemia? *

Acute Kidney Failure: 10 people, 66.67%
Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 8 people, 53.33%
Bone Disorder: 8 people, 53.33%
Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 8 people, 53.33%
Mental Status Changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation): 8 people, 53.33%
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 8 people, 53.33%
Hyperlipidaemia (presence of excess lipids in the blood): 8 people, 53.33%
Hypercapnia (too much smoke): 7 people, 46.67%
Femur Fracture: 7 people, 46.67%
Coronary Artery Embolism (blockage of artery of heart): 7 people, 46.67%

What are the existing conditions these people have? *

Osteoporosis (bones weak and more likely to break): 7 people, 46.67%
Osteopenia (a condition where bone mineral density is lower than normal): 7 people, 46.67%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 2 people, 13.33%
Colon Cancer Metastatic (cancer of colon spreads to other part of body): 2 people, 13.33%
Muscle Spasms (muscle contraction): 2 people, 13.33%
Sleep Disorder: 2 people, 13.33%
Migraine (headache): 2 people, 13.33%
Lung Cancer - Non-Small Cell (lung cancer): 2 people, 13.33%
High Blood Cholesterol: 1 person, 6.67%
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

Do you take Dilantin and have Hypomagnesaemia?

- Check whether Hypomagnesaemia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Dilantin:

Dilantin (20,858 reports)

Hypomagnesaemia treatments and more:

Hypomagnesaemia (18,707 reports)

Browse all side effects of Dilantin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hypomagnesaemia:

Hypomagnesaemia (1,030 drugs)

Browse all the conditions that are associated with Hypomagnesaemia:

Hypomagnesaemia (1,053 conditions)

Related publications that referenced our studies

Akasaka E, Kayo SJ, Nakano H, Ishii N, Hashimoto T, Sawamura D, "Diaminodiphenyl Sulfone-Induced Hemolytic Anemia and Alopecia in a Case of Linear IgA Bullous Dermatosis", Case reports in dermatology, 2014 Jan .
Akasaka E, Kayo SJ, Nakano H, Ishii N, Hashimoto T, Sawamura D, "Diaminodiphenyl Sulfone-Induced Hemolytic Anemia and Alopecia in a Case of Linear IgA Bullous Dermatosis", Case reports in dermatology, 2014 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on phenytoin sodium (the active ingredients of Dilantin) and Dilantin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.