Dilantin and Thinking abnormal - a phase IV clinical study of FDA data

Summary:

Thinking abnormal is reported as a side effect among people who take Dilantin (phenytoin sodium), especially for people who are female, 60+ old, have been taking the drug for 2 - 5 years also take Keppra, and have Convulsion.

The phase IV clinical study analyzes which people have Thinking abnormal when taking Dilantin. It is created by eHealthMe based on reports of 19,857 people who have side effects when taking Dilantin from the FDA, and is updated regularly.

What is Dilantin?

Dilantin has active ingredients of phenytoin sodium. It is often used in epilepsy. eHealthMe is studying from 20,859 Dilantin users. Check the latest studies of Dilantin.

What is Thinking abnormal?

Thinking abnormal is found to be associated with 1,060 drugs and 1,185 conditions by eHealthMe. Check the latest studies of Thinking abnormal.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

19,857 people reported to have side effects when taking Dilantin.
Among them, 63 people (0.32%) have Thinking abnormal.

Among these 63 people:

How long have people been on Dilantin when they have Thinking abnormal? *

What is the gender of people who have Thinking abnormal when taking Dilantin? *

female: 65.08 %
male: 34.92 %

What is the age of people who have Thinking abnormal when taking Dilantin? *

What are other drugs people take besides Dilantin? *

What are other side effects people have besides Thinking abnormal? *

Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 26 people, 41.27%
Dizziness: 21 people, 33.33%
Feeling Abnormal: 20 people, 31.75%
Weakness: 16 people, 25.40%
Headache (pain in head): 15 people, 23.81%
Balance Disorder: 15 people, 23.81%
Pain: 14 people, 22.22%
Fatigue (feeling of tiredness): 14 people, 22.22%
Nausea (feeling of having an urge to vomit): 14 people, 22.22%
Malaise (a feeling of general discomfort or uneasiness): 12 people, 19.05%

What are the existing conditions these people have? *

Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 17 people, 26.98%
Grand Mal Convulsion (a type of generalized seizure that affects the entire brain): 6 people, 9.52%
Pain: 5 people, 7.94%
High Blood Cholesterol: 3 people, 4.76%
Ill-Defined Disorder: 3 people, 4.76%
Attention Deficit Hyperactivity Disorder (a chronic condition including attention difficulty, hyperactivity, and impulsiveness): 2 people, 3.17%
Muscle Spasms (muscle contraction): 2 people, 3.17%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 2 people, 3.17%
Bipolar Disorder (mood disorder): 2 people, 3.17%
Quit Smoking: 2 people, 3.17%

* Approximation only. Some reports may have incomplete information.

Do you take Dilantin and have Thinking abnormal?

- Check whether Thinking abnormal is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Dilantin:

Dilantin (20,859 reports)

Browse all side effects of Dilantin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Thinking abnormal:

Thinking abnormal (1,060 drugs)

Browse all the conditions that are associated with Thinking abnormal:

Thinking abnormal (1,185 conditions)

Related publications that referenced our studies

Akasaka E, Kayo SJ, Nakano H, Ishii N, Hashimoto T, Sawamura D, "Diaminodiphenyl Sulfone-Induced Hemolytic Anemia and Alopecia in a Case of Linear IgA Bullous Dermatosis", Case reports in dermatology, 2014 Jan .
Akasaka E, Kayo SJ, Nakano H, Ishii N, Hashimoto T, Sawamura D, "Diaminodiphenyl Sulfone-Induced Hemolytic Anemia and Alopecia in a Case of Linear IgA Bullous Dermatosis", Case reports in dermatology, 2014 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on phenytoin sodium (the active ingredients of Dilantin) and Dilantin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.