Dilantin and Thyroid function test abnormal - a phase IV clinical study of FDA data

Summary:

Thyroid function test abnormal is reported as a side effect among people who take Dilantin (phenytoin sodium), especially for people who are female, 60+ old, also take Synthroid, and have Convulsion.

The phase IV clinical study analyzes which people have Thyroid function test abnormal when taking Dilantin. It is created by eHealthMe based on reports of 19,857 people who have side effects when taking Dilantin from the FDA, and is updated regularly.

What is Dilantin?

Dilantin has active ingredients of phenytoin sodium. It is often used in epilepsy. eHealthMe is studying from 20,858 Dilantin users. Check the latest studies of Dilantin.

What is Thyroid function test abnormal?

Thyroid function test abnormal is found to be associated with 1,602 drugs and 1,602 conditions by eHealthMe. Check the latest studies of Thyroid function test abnormal.

On May, 07, 2026

19,857 people reported to have side effects when taking Dilantin.
Among them, 31 people (0.16%) have Thyroid function test abnormal.

Could Dilantin cause Thyroid function test abnormal?

Among these 31 people:

What is the gender of people who have Thyroid function test abnormal when taking Dilantin? *

female: 80.65 %
male: 19.35 %

What is the age of people who have Thyroid function test abnormal when taking Dilantin? *

What are other drugs people take besides Dilantin? *

What are other side effects people have besides Thyroid function test abnormal? *

Fatigue (feeling of tiredness): 8 people, 25.81%
Weight Decreased: 8 people, 25.81%
Malaise (a feeling of general discomfort or uneasiness): 7 people, 22.58%
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 7 people, 22.58%
Heart Attack: 6 people, 19.35%
Dizziness: 6 people, 19.35%
Rashes (redness): 6 people, 19.35%
Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 5 people, 16.13%
Drowsiness: 5 people, 16.13%
Loss Of Consciousness: 5 people, 16.13%

What are the existing conditions these people have? *

Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 16 people, 51.61%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 2 people, 6.45%
Muscle Spasms (muscle contraction): 1 person, 3.23%
Attention Deficit Hyperactivity Disorder (a chronic condition including attention difficulty, hyperactivity, and impulsiveness): 1 person, 3.23%
Depression: 1 person, 3.23%
Grand Mal Convulsion (a type of generalized seizure that affects the entire brain): 1 person, 3.23%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 1 person, 3.23%
Ill-Defined Disorder: 1 person, 3.23%
Major Depression (a mood state that goes well beyond temporarily feeling sad or blue. it is a serious medical illness that affects one's thoughts, feelings): 1 person, 3.23%
Mood Swings (an extreme or rapid change in mood): 1 person, 3.23%

* Approximation only. Some reports may have incomplete information.

Do you take Dilantin and have Thyroid function test abnormal?

- Check whether Thyroid function test abnormal is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Dilantin:

Dilantin (20,858 reports)

Browse all side effects of Dilantin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Thyroid function test abnormal:

Thyroid function test abnormal (1,602 drugs)

Browse all the conditions that are associated with Thyroid function test abnormal:

Thyroid function test abnormal (1,602 conditions)

Related publications that referenced our studies

Akasaka E, Kayo SJ, Nakano H, Ishii N, Hashimoto T, Sawamura D, "Diaminodiphenyl Sulfone-Induced Hemolytic Anemia and Alopecia in a Case of Linear IgA Bullous Dermatosis", Case reports in dermatology, 2014 Jan .
Akasaka E, Kayo SJ, Nakano H, Ishii N, Hashimoto T, Sawamura D, "Diaminodiphenyl Sulfone-Induced Hemolytic Anemia and Alopecia in a Case of Linear IgA Bullous Dermatosis", Case reports in dermatology, 2014 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on phenytoin sodium (the active ingredients of Dilantin) and Dilantin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.