Dimenhydrinate and Hepatic encephalopathy - a phase IV clinical study of FDA data

Summary:

Hepatic encephalopathy is reported as a side effect among people who take Dimenhydrinate (dimenhydrinate), especially for people who are male, 60+ old, also take Acetaminophen, and have Abdominal pain.

The phase IV clinical study analyzes which people have Hepatic encephalopathy when taking Dimenhydrinate. It is created by eHealthMe based on reports of 6,546 people who have side effects when taking Dimenhydrinate from the FDA, and is updated regularly.

What is Dimenhydrinate?

Dimenhydrinate has active ingredients of dimenhydrinate. It is often used in nausea. eHealthMe is studying from 6,644 Dimenhydrinate users. Check the latest studies of Dimenhydrinate.

What is Hepatic encephalopathy?

Hepatic encephalopathy (spectrum of neuropsychiatric abnormalities in patients with liver failure) is found to be associated with 909 drugs and 1,264 conditions by eHealthMe. Check the latest studies of Hepatic encephalopathy.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 23, 2026

6,546 people reported to have side effects when taking Dimenhydrinate.
Among them, 11 people (0.17%) have Hepatic encephalopathy.

Could Dimenhydrinate cause Hepatic encephalopathy?

Among these 11 people:

What is the gender of people who have Hepatic encephalopathy when taking Dimenhydrinate? *

female: 45.45 %
male: 54.55 %

What is the age of people who have Hepatic encephalopathy when taking Dimenhydrinate? *

What are other drugs people take besides Dimenhydrinate? *

What are other side effects people have besides Hepatic encephalopathy? *

Hepatic Failure (liver failure): 6 people, 54.55%
Ascites (accumulation of fluid in the abdominal cavity): 4 people, 36.36%
Diarrhea: 4 people, 36.36%
Agitation (state of anxiety or nervous excitement): 3 people, 27.27%
Gallstones (stone formation by bile component): 3 people, 27.27%
Blood Bilirubin Increased: 3 people, 27.27%
Mouth Haemorrhage (bleeding from mouth): 3 people, 27.27%
Enanthema (rash formed inside the body): 2 people, 18.18%
Mean Arterial Pressure Decreased (less than an average blood pressure in an individual): 2 people, 18.18%
Hepatic Steatosis (fatty liver disease): 2 people, 18.18%

What are the existing conditions these people have? *

Swallowing Difficulty: 3 people, 27.27%
Hepatic Neoplasm Malignant (liver cancer): 3 people, 27.27%
Dizziness: 3 people, 27.27%
Diarrhea: 3 people, 27.27%
Conjunctivitis (pink eye): 3 people, 27.27%
Breast Cancer: 3 people, 27.27%
Abdominal Pain: 3 people, 27.27%
Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 1 person, 9.09%
Schizoaffective Disorder (a mental disorder characterized by disordered thought): 1 person, 9.09%
Rhinitis (a medical term for irritation and inflammation of the mucous membrane inside the nose): 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Dimenhydrinate and have Hepatic encephalopathy?

- Check whether Hepatic encephalopathy is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Dimenhydrinate:

Dimenhydrinate (6,644 reports)

Browse all side effects of Dimenhydrinate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hepatic encephalopathy:

Hepatic encephalopathy (909 drugs)

Browse all the conditions that are associated with Hepatic encephalopathy:

Hepatic encephalopathy (1,264 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on dimenhydrinate (the active ingredients of Dimenhydrinate) and Dimenhydrinate (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.